Post-partum haemorrhage is the leading cause of maternal mortality globally.¹ The majority of deaths resulting from post-partum haemorrhage occur during the first 24 h after birth, most of which could be avoided by routine prevention through active management of the third stage of labour and prompt and effective management of post-partum haemorrhage, including the use of uterotonics and fluid replacement. Tranexamic acid, an antifibrinolytic drug, was identified as a promising candidate to be included in recommended packages for treatment of post-partum haemorrhage, since it has shown efficacy in reducing blood loss and mortality following surgical trauma.

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世卫组织关于静脉注射氨甲环酸治疗产后出血的更新建议

产后出血是全球孕产妇死亡的主要原因。¹产后出血导致的大多数死亡发生在出生后的头 24 小时内，通过积极管理第三产程和及时有效地管理产后出血，常规预防可以避免大部分死亡，包括使用宫缩剂和补液。氨甲环酸是一种抗纤维蛋白溶解药物，被认为是一种很有前途的候选药物，可被纳入治疗产后出血的推荐方案中，因为它已显示出减少手术创伤后失血和死亡率的功效。