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Graphene quantum dots based fluorescence turn-on nanoprobe for highly sensitive and selective imaging of hydrogen sulfide in living cells†
Biomaterials Science ( IF 6.6 ) Pub Date : 2017-11-01 00:00:00 , DOI: 10.1039/c7bm00818j Nan Li 1, 2, 3, 4, 5 , Aung Than 6, 7, 8, 9 , Jie Chen 6, 7, 8, 9 , Fengna Xi 5, 10, 11, 12, 13 , Jiyang Liu 5, 10, 11, 12, 13 , Peng Chen 6, 7, 8, 9
Biomaterials Science ( IF 6.6 ) Pub Date : 2017-11-01 00:00:00 , DOI: 10.1039/c7bm00818j Nan Li 1, 2, 3, 4, 5 , Aung Than 6, 7, 8, 9 , Jie Chen 6, 7, 8, 9 , Fengna Xi 5, 10, 11, 12, 13 , Jiyang Liu 5, 10, 11, 12, 13 , Peng Chen 6, 7, 8, 9
Affiliation
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Hydrogen sulfide (H2S), being an important gaseous signaling molecule, has been gaining increasing attention for its involvement in a wide range of physiological processes. Herein, we developed a novel fluorescence turn-on nanoprobe for selective and sensitive detection of H2S based on graphene quantum dots (GQDs) conjugated with (2,4-dinitrophenoxy)tyrosine (DNPTYR). Taking advantage of its high fluorescence quantum yield, biocompatibility, photostability, and ease to be uptaken by cells, the GQD-based fluorescence probe was further employed for real-time monitoring of the triggered dynamic change of the intracellular H2S level in live cells.
中文翻译：
基于石墨烯量子点的荧光开启纳米探针，用于活细胞中硫化氢的高灵敏度和选择性成像†
硫化氢（H 2 S）是一种重要的气体信号分子，由于其参与广泛的生理过程而受到越来越多的关注。在这里，我们开发了一种新颖的荧光纳米探针，用于基于与（2,4-二硝基苯氧基）酪氨酸（DNPTYR）共轭的石墨烯量子点（GQDs）进行H 2 S的选择性和灵敏检测。利用其高荧光量子产率，生物相容性，光稳定性和易于被细胞吸收的特性，基于GQD的荧光探针被进一步用于实时监测活细胞中细胞内H 2 S水平触发的动态变化。。
更新日期：2017-11-01
中文翻译：
基于石墨烯量子点的荧光开启纳米探针，用于活细胞中硫化氢的高灵敏度和选择性成像†
硫化氢（H 2 S）是一种重要的气体信号分子，由于其参与广泛的生理过程而受到越来越多的关注。在这里，我们开发了一种新颖的荧光纳米探针，用于基于与（2,4-二硝基苯氧基）酪氨酸（DNPTYR）共轭的石墨烯量子点（GQDs）进行H 2 S的选择性和灵敏检测。利用其高荧光量子产率，生物相容性，光稳定性和易于被细胞吸收的特性，基于GQD的荧光探针被进一步用于实时监测活细胞中细胞内H 2 S水平触发的动态变化。。
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