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Anti-CRISPR: discovery, mechanism and function
Nature Reviews Microbiology ( IF 88.1 ) Pub Date : 2017-10-24 , DOI: 10.1038/nrmicro.2017.120 April Pawluk , Alan R. Davidson , Karen L. Maxwell
Nature Reviews Microbiology ( IF 88.1 ) Pub Date : 2017-10-24 , DOI: 10.1038/nrmicro.2017.120 April Pawluk , Alan R. Davidson , Karen L. Maxwell
Anti-CRISPR: discovery, mechanism and function
中文翻译:
抗CRISPR:发现,机制和功能
抗CRISPR:发现,机制和功能
更新日期:2017-10-30
Nature Reviews Microbiology, Published online: 24 October 2017; doi:10.1038/nrmicro.2017.120
CRISPR–Cas adaptive immune systems are widespread in prokaryotes. In this Progress article, Maxwell and colleagues highlight how phages and other mobile genetic elements inactivate CRISPR–Cas systems using anti-CRISPR proteins and outline evolutionary and biotechnological implications of anti-CRISPR protein activity.
中文翻译:
抗CRISPR:发现,机制和功能
抗CRISPR:发现,机制和功能
《自然评论微生物学》,在线发布:2017年10月24日; doi:10.1038 / nrmicro.2017.120
CRISPR-Cas适应性免疫系统广泛存在于原核生物中。Maxwell及其同事在本文中强调了噬菌体和其他移动遗传元件如何使用抗CRISPR蛋白质灭活CRISPR-Cas系统,并概述了抗CRISPR蛋白质活性的进化和生物技术意义。