A highly enantioselective Rh-catalyzed addition of arylboronic acids to non-benzofused five-membered cyclic N-sulfonyl alkyl-substituted ketimines has been developed. With simple chiral sulfur-olefin as the ligand, the reaction allows convenient access to a variety of sulfamidates with uniformly excellent enantioselectivities (97–99% ee). The synthetic utility of this protocol was exemplified by rapid asymmetric construction of tetrasubstituted chiral β-amino alcohols and their derivatives.

中文翻译：

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烷基取代的非苯并稠合环状N-磺酰基酮亚胺的高对映选择性Rh /手性硫-烯烃催化的芳基化

已经开发了高度对映体的Rh催化的芳基硼酸加成到非苯并稠合的五元环状N-磺酰基烷基取代的酮亚胺上。用简单的手性硫-烯烃作为配体，该反应可方便地获得具有统一优异对映选择性（97-99％ee）的各种氨基磺酸盐。该方案的合成效用以四取代的手性β-氨基醇及其衍生物的快速不对称结构为例。