Fixed for function: Four dehydrogenases (7α-HSDH, LDH, 7β-HSDH, and GDH) were co-immobilized pairwise on an epoxy-functionalized resin. A cascade of two packed-bed reactors of these co-immobilized enzymes allow continuous synthesis of ursodeoxycholic acid (UDCA) from the cheap and easily available chenodeoxycholic acid (CDCA).

中文翻译：

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通过使用两个固定化酶的级联反应器连续生产熊去氧胆酸

功能固定：将四种脱氢酶（7α-HSDH，LDH，7β-HSDH和GDH）成对共固定在环氧官能化树脂上。这些共固定化酶的两个填充床反应器级联，可以从便宜且容易获得的鹅去氧胆酸（CDCA）连续合成熊去氧胆酸（UDCA）。