The discovery of a small molecule inhibitor that targets the inflammasome sensor NLRP3 offers a new path for the development of selective inflammasome blockers with potential therapeutic benefit in a wide range of human diseases (in this issue, see Jiang et al., https://doi.org/10.1084/jem.20171419).

中文翻译：

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NLRP3 抑制的新线索

针对炎症小体传感器 NLRP3 的小分子抑制剂的发现，为选择性炎症小体阻断剂的开发提供了新途径，对多种人类疾病具有潜在的治疗益处（本期参见 Jiang 等人，https: // doi.org/10.1084/jem.20171419）。