Klebsiella pneumoniae is a Gram-negative facultative anaerobe that metabolizes glycerol efficiently under both aerobic and anaerobic conditions. This microbe is considered an outstanding biocatalyst for transforming glycerol into a variety of value-added products. Crude glycerol is a cheap carbon source and can be converted by K. pneumoniae into useful compounds such as lactic acid, 3-hydroxypropionic acid, ethanol, 1,3-propanediol, 2,3-butanediol, and succinic acid. This review summarizes glycerol metabolism in K. pneumoniae and its potential as a microbial cell factory for the production of commercially important acids and alcohols. Although many challenges remain, K. pneumoniae is a promising workhorse when glycerol is used as the carbon source.

肺炎克雷伯氏菌是革兰氏阴性兼性厌氧菌，在需氧和厌氧条件下均能高效代谢甘油。该微生物被认为是将甘油转化为多种增值产品的杰出生物催化剂。粗甘油是一种廉价的碳源，可以被肺炎克雷伯菌转化为有用的化合物，例如乳酸，3-羟基丙酸，乙醇，1,3-丙二醇，2,3-丁二醇和琥珀酸。这篇综述总结了肺炎克雷伯菌中的甘油代谢及其作为微生物细胞工厂生产商业上重要的酸和醇的潜力。尽管仍然存在许多挑战，但肺炎克雷伯菌 当甘油用作碳源时，它是有前途的主力军。