The demand for effective eye therapies is driving the development of injectable hydrogels as new medical devices for controlled delivery and filling purposes. This article introduces the properties of injectable hydrogels and summarizes their versatile application in the treatment of ophthalmic diseases, including age-related macular degeneration, cataracts, diabetic retinopathy, glaucoma, and intraocular cancers. A number of injectable hydrogels are approved by FDA as surgery sealants, tissue adhesives, and are now being investigated as a vitreous humor substitute. Research on hydrogels for drug, factor, nanoparticle, and stem cell delivery is still under pre-clinical investigation or in clinical trials. Although substantial progress has been achieved using injectable hydrogels, some challenging issues must still be overcome before they can be effectively used in medical practice.

对有效眼部治疗的需求正在推动可注射水凝胶作为用于受控输送和填充目的的新型医疗设备的发展。本文介绍了可注射水凝胶的特性，并总结了其在治疗老年性黄斑变性、白内障、糖尿病视网膜病变、青光眼和眼内癌等眼科疾病中的广泛应用。许多可注射水凝胶已被 FDA 批准用作手术密封剂、组织粘合剂，目前正在研究作为玻璃体液的替代品。用于药物、因子、纳米颗粒和干细胞递送的水凝胶研究仍处于临床前研究或临床试验阶段。尽管使用可注射水凝胶取得了实质性进展，