Overdiagnosis is the main harm of cancer screening programs but is difficult to quantify. This review aims to evaluate existing approaches to estimate the magnitude of overdiagnosis in cancer screening in order to gain insight into the strengths and limitations of these approaches and to provide researchers with guidance to obtain reliable estimates of overdiagnosis in cancer screening.

中文翻译：

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量化癌症筛查中的过度诊断：评估方法学的系统评价

过度诊断是癌症筛查程序的主要危害，但难以量化。这篇综述旨在评估现有方法，以评估癌症筛查中过度诊断的程度，以便深入了解这些方法的优势和局限性，并为研究人员提供指导，以获得对癌症筛查中过度诊断的可靠估计。