当前位置: X-MOL 学术ACS Synth. Biol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Genetic Constructor: An Online DNA Design Platform
ACS Synthetic Biology ( IF 4.7 ) Pub Date : 2017-10-20 00:00:00 , DOI: 10.1021/acssynbio.7b00236
Maxwell Bates 1 , Joe Lachoff 1 , Duncan Meech 1 , Valentin Zulkower 2 , Anaïs Moisy 2 , Yisha Luo 2 , Hille Tekotte 2 , Cornelia Johanna Franziska Scheitz 1 , Rupal Khilari 1 , Florencio Mazzoldi 1 , Deepak Chandran 3 , Eli Groban 1
Affiliation  

Genetic Constructor is a cloud Computer Aided Design (CAD) application developed to support synthetic biologists from design intent through DNA fabrication and experiment iteration. The platform allows users to design, manage, and navigate complex DNA constructs and libraries, using a new visual language that focuses on functional parts abstracted from sequence. Features like combinatorial libraries and automated primer design allow the user to separate design from construction by focusing on functional intent, and design constraints aid iterative refinement of designs. A plugin architecture enables contributions from scientists and coders to leverage existing powerful software and connect to DNA foundries. The software is easily accessible and platform agnostic, free for academics, and available in an open-source community edition. Genetic Constructor seeks to democratize DNA design, manufacture, and access to tools and services from the synthetic biology community.

中文翻译:

Genetic Constructor:在线 DNA 设计平台

Genetic Constructor 是一款云计算机辅助设计 (CAD) 应用程序,旨在支持合成生物学家从设计意图到 DNA 制造和实验迭代。该平台允许用户使用一种新的视觉语言来设计、管理和导航复杂的 DNA 结构和库,该语言专注于从序列中提取的功能部分。组合库和自动引物设计等功能允许用户通过关注功能意图将设计与构建分开,设计约束有助于设计的迭代细化。插件架构使科学家和编码人员能够利用现有的强大软件并连接到 DNA 铸造厂。该软件易于访问且与平台无关,对学术界免费,并提供开源社区版本。Genetic Constructor 致力于实现 DNA 设计、制造以及合成生物学界工具和服务的民主化。
更新日期:2017-10-20
down
wechat
bug