Photomorphogenesis is oppositely regulated by two groups of transcription factors. CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) degrades the positive factors but stabilizes the negative ones to predominantly repress photomorphogenesis. It is known that COP1 degrades substrates as an E3 ligase. Two recent studies unraveled the long-sought mechanisms of how COP1 stabilizes the negative transcription factors.

中文翻译：

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通过E3连接酶COP1稳定转录因子

光形态发生由两组转录因子相反地调节。本构光生质1（COP1）可降解正性因子，但可稳定负性因子，从而主要抑制光形态发生。已知COP1降解底物作为E3连接酶。最近的两项研究揭示了COP1稳定负转录因子的长期机制。