Rationale. The value of microRNAs (miRNAs) as biomarkers has been addressed in various clinical contexts. Initial studies suggested that miRNAs, such as the brain-enriched miR-124-3p, might improve outcome prediction after out-of-hospital cardiac arrest. The aim of this study is to determine the prognostic value of miR-122-5p in a large cohort of comatose survivors of out-of-hospital cardiac arrest.

中文翻译：

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出院后心脏骤停后循环MiR-122-5p预测结果的增量值

基本原理。microRNA（miRNA）作为生物标志物的价值已在各种临床背景下得到了解决。最初的研究表明，miRNA，例如富含脑的miR-124-3p，可能会改善院外心脏骤停后的预后。这项研究的目的是确定miR-122-5p在院外心脏骤停的大量昏迷幸存者中的预后价值。