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Advances in Alzheimer’s Diagnosis and Therapy: The Implications of Nanotechnology
Trends in Biotechnology ( IF 17.3 ) Pub Date : 2017-06-27 , DOI: 10.1016/j.tibtech.2017.06.002
Mohammad Javad Hajipour , Michelle R. Santoso , Farhad Rezaee , Haniyeh Aghaverdi , Morteza Mahmoudi , George Perry

Alzheimer’s disease (AD) is a type of dementia that causes major issues for patients’ memory, thinking, and behavior. Despite efforts to advance AD diagnostic and therapeutic tools, AD remains incurable due to its complex and multifactorial nature and lack of effective diagnostics/therapeutics. Nanoparticles (NPs) have demonstrated the potential to overcome the challenges and limitations associated with traditional diagnostics/therapeutics. Nanotechnology is now offering new tools and insights to advance our understanding of AD and eventually may offer new hope to AD patients. Here, we review the key roles of nanotechnologies in the recent literature, in both diagnostic and therapeutic aspects of AD, and discuss how these achievements may improve patient prognosis and quality of life.



中文翻译:

阿尔茨海默氏病的诊断和治疗进展:纳米技术的含义。

阿尔茨海默氏病(AD)是一种痴呆症,会引起患者记忆,思维和行为方面的重大问题。尽管人们在努力提高AD的诊断和治疗工具的水平,但由于AD的复杂和多因素性质以及缺乏有效的诊断/治疗手段,AD仍然无法治愈。纳米颗粒(NPs)已显示出克服与传统诊断/治疗方法相关的挑战和局限性的潜力。纳米技术现在正在提供新的工具和见解,以加深我们对AD的了解,并最终可能为AD患者带来新的希望。在这里,我们回顾了纳米技术在AD的诊断和治疗方面的最新文献中的关键作用,并讨论了这些成就如何改善患者的预后和生活质量。

更新日期:2017-06-27
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