A new tunable Cu(I)-catalyzed site-selective dehydrogenative amination of β,γ-unsaturated hydrazones has been established using readily accessible dioxygen as a green oxidant. The presence of Cu₂O/O₂ regiospecifically accessed densely functionalized pyrazol-4-ones with one quaternary carbon-amino functionality, in which O₂ acted as both a reaction component and an oxidant, whereas the employment of CuI/O₂ as a catalytic oxidation system resulted in 1,6-dihydropyradazines with good yields.

中文翻译：

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可调谐的Cu（i）催化β，γ-不饱和azo的位点选择性脱氢胺化，用于吡唑-4-酮和1,6-二氢吡嗪的发散合成†

使用容易获得的双氧作为绿色氧化剂，已经建立了一种新的可调谐的Cu（I）催化的β，γ-不饱和azo酮的位点选择性脱氢胺化反应。Cu ₂ O / O ₂区域特异性地访问具有一个季碳-氨基官能团的致密官能化的吡唑-4-酮，其中O ₂既是反应组分又是氧化剂，而使用CuI / O ₂作为氧化剂。催化氧化反应制得的1,6-二氢吡嗪类化合物收率很高。