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Size matters: Finding growth pathways that protect the heart.
Cell Research ( IF 44.1 ) Pub Date : 2017-Oct-01 , DOI: 10.1038/cr.2017.120
J Sawalla Guseh , Anthony Rosenzweig

In a recent paper published in Cell Research, Abdul-Ghani and colleagues show that the cytokine, cardiotrophin-1 (CT1), drives a protective form of reversible cardiac hypertrophy that acts through a nonapoptotic caspase-dependent mechanism. Since CT1 can be delivered as exogenous protein, these studies provide new biological insights and potential translational opportunities.

中文翻译:

大小很重要:寻找保护心脏的生长途径。

在最近发表在《细胞研究》上的一篇论文中,Abdul-Ghani及其同事表明,细胞因子心肌营养素1(CT1)驱动一种可逆性心肌肥大的保护性形式,该形式通过非凋亡的caspase依赖性机制起作用。由于CT1可以作为外源蛋白提供,因此这些研究提供了新的生物学见解和潜在的翻译机会。
更新日期:2017-09-22
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