The present paper provides a review of the current knowledge relating to the health benefits of probiotics, specially focused on the effects they may have together with physical exercise on mood disorders and related chronic medical conditions.With both these conditions being a substantial contributor to the global disease burden, any alternative therapy must be considered. Probiotics influence the gut microbiota through a complex network of events which can influence mechanisms leading to development of mood disorders such as depression and anxiety. Similarly, through a complex interaction between psychological and neurobiological mechanisms, exercise has been found to play a key role in mood enhancement.

本文概述了有关益生菌对健康有益的最新知识，特别是侧重于益生菌以及体育锻炼对情绪障碍和相关的慢性医学状况可能产生的影响，这两种状况都是对全球健康的重要贡献疾病负担，必须考虑任何替代疗法。益生菌通过复杂的事件网络影响肠道菌群，这些事件可以影响导致情绪障碍（如抑郁和焦虑）发展的机制。同样，通过心理和神经生物学机制之间的复杂相互作用，人们发现运动在情绪改善中起着关键作用。