Spinal cord injury (SCI) is a complex pathology that evolves after primary acute mechanical injury, causing further damage to the spinal cord tissue that exacerbates clinical outcomes. Based on encouraging results from preclinical experiments, some cell treatments being translated into clinical practice demonstrate promising and effective improvement in sensory/motor function. Combinatorial treatments of cell and drug/biological factors have been demonstrated to be more effective than cell treatments alone. Recent advances have led to the development of biomaterials aiming to promote in situ cell delivery for SCI, together with combinatorial strategies using drugs/biomolecules to achieve a maximized multitarget approach. This review provides an overview of single and combinatorial regenerative cell treatments as well as potential delivery options to treat SCI.

脊髓损伤（SCI）是一种复杂的病理，在原发性急性机械损伤后会演变成一种对脊髓组织造成进一步损害的疾病，从而加剧临床结果。基于临床前实验的令人鼓舞的结果，一些细胞治疗已转化为临床实践，证明其在感觉/运动功能方面有希望且有效的改善。已经证明细胞和药物/生物因子的组合治疗比单独的细胞治疗更有效。最近的进展导致旨在促进就地推广的生物材料的发展SCI的细胞递送，以及使用药物/生物分子的组合策略以实现最大化的多靶点方法。这篇综述概述了单一和组合的再生细胞治疗以及治疗SCI的潜在方法。