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The Sleeping Cerebellum
Trends in Neurosciences ( IF 15.9 ) Pub Date : 2017-05-01 , DOI: 10.1016/j.tins.2017.03.001
Cathrin B. Canto , Yoshiyuki Onuki , Bastiaan Bruinsma , Ysbrand D. van der Werf , Chris I. De Zeeuw

We sleep almost one-third of our lives and sleep plays an important role in critical brain functions like memory formation and consolidation. The role of sleep in cerebellar processing, however, constitutes an enigma in the field of neuroscience; we know little about cerebellar sleep-physiology, cerebro-cerebellar interactions during sleep, or the contributions of sleep to cerebellum-dependent memory consolidation. Likewise, we do not understand why cerebellar malfunction can lead to changes in the sleep-wake cycle and sleep disorders. In this review, we evaluate how sleep and cerebellar processing may influence one another and highlight which scientific routes and technical approaches could be taken to uncover the mechanisms underlying these interactions.

中文翻译:

沉睡的小脑

我们一生中几乎有三分之一的时间都在睡觉,而睡眠在记忆形成和巩固等关键的大脑功能中起着重要作用。然而,睡眠在小脑处理中的作用在神经科学领域是一个谜。我们对小脑睡眠生理学、睡眠期间的脑-小脑相互作用或睡眠对小脑依赖性记忆巩固的贡献知之甚少。同样,我们不明白为什么小脑功能障碍会导致睡眠-觉醒周期和睡眠障碍的变化。在这篇综述中,我们评估了睡眠和小脑处理如何相互影响,并强调可以采取哪些科学途径和技术方法来揭示这些相互作用的潜在机制。
更新日期:2017-05-01
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