Adjuvants incorporated in prophylactic and/or therapeutic vaccine formulations impact vaccine efficacy by enhancing, modulating, and/or prolonging the immune response. In addition, they reduce antigen concentration and the number of immunizations required for protective efficacy, therefore contributing to making vaccines more cost effective. Our better understanding of the molecular mechanisms of immune recognition and protection has led research efforts to develop new adjuvants that are currently at various stages of development or clinical evaluation. In this review, we focus mainly on several of these promising adjuvants, and summarize recent work conducted in various laboratories to develop novel lipid-containing adjuvants

预防和/或治疗性疫苗制剂中掺入的佐剂通过增强，调节和/或延长免疫应答来影响疫苗效力。另外，它们降低了抗原浓度和保护效力所需的免疫次数，因此有助于使疫苗更具成本效益。我们对免疫识别和保护的分子机制的更好理解促使研究人员开发了新的佐剂，这些佐剂目前处于开发或临床评估的各个阶段。在这篇综述中，我们主要关注这些有前途的佐剂中的几种，并总结了在各个实验室中为开发新型含脂佐剂而开展的最新工作。