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A Viro-Immunotherapy Triple Play for the Treatment of Glioblastoma.
Cancer Cell ( IF 50.3 ) Pub Date : 2017-08-14 , DOI: 10.1016/j.ccell.2017.07.012
John C. Bell , Carolina S. Ilkow

In this issue of Cancer Cell, Saha et al. systematically test and optimize combination therapy strategies in a challenging model of glioblastoma. Durable complete responses were seen only when an oncolytic virus expressing IL12 was coupled with anti-CTLA-4 and anti-PD-1 therapeutics.

中文翻译:

病毒免疫疗法三重疗法治疗胶质母细胞瘤。

在本期《癌细胞》中,Saha等人。在具有挑战性的胶质母细胞瘤模型中系统地测试和优化组合治疗策略。仅当表达IL12的溶瘤病毒与抗CTLA-4和抗PD-1治疗剂偶联时,才能看到持久的完全应答。
更新日期:2017-08-14
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