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New Views into the Genetic Landscape of Metastatic Breast Cancer.
Cancer Cell ( IF 50.3 ) Pub Date : 2017-08-14 , DOI: 10.1016/j.ccell.2017.07.011
Xiaoyu Zhao , Scott Powers

Whether metastasis-specific genetic alterations exist remains controversial. The study by Yates et al. in this issue of Cancer Cell provides evidence that metastases emerge late during primary breast cancer progression and that additional driver mutations are often acquired, posing both challenges and opportunities for precision treatment of metastatic breast cancer.

中文翻译:

转移性乳腺癌遗传学新观点。

是否存在转移特异性遗传改变仍存在争议。Yates等人的研究。本期《癌细胞》杂志提供的证据表明,转移在原发性乳腺癌进展过程中出现得较晚,并且经常获得其他驱动突变,这为转移性乳腺癌的精确治疗带来了挑战和机遇。
更新日期:2017-08-14
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