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4D printing of polymeric materials for tissue and organ regeneration
Materials Today ( IF 24.2 ) Pub Date : 2017-12-01 , DOI: 10.1016/j.mattod.2017.06.005
Shida Miao 1 , Nathan Castro 1, 2 , Margaret Nowicki 1 , Lang Xia 1 , Haitao Cui 1 , Xuan Zhou 1 , Wei Zhu 1 , Se-Jun Lee 1 , Kausik Sarkar 1 , Giovanni Vozzi 3 , Yasuhiko Tabata 4 , John Fisher 5 , Lijie Grace Zhang 1, 6, 7
Affiliation  

Four dimensional (4D) printing is an emerging technology with great capacity for fabricating complex, stimuli-responsive 3D structures, providing great potential for tissue and organ engineering applications. Although the 4D concept was first highlighted in 2013, extensive research has rapidly developed, along with more-in-depth understanding and assertions regarding the definition of 4D. In this review, we begin by establishing the criteria of 4D printing, followed by an extensive summary of state-of-the-art technological advances in the field. Both transformation-preprogrammed 4D printing and 4D printing of shape memory polymers are intensively surveyed. Afterwards we will explore and discuss the applications of 4D printing in tissue and organ regeneration, such as developing synthetic tissues and implantable scaffolds, as well as future perspectives and conclusions.

中文翻译:

用于组织和器官再生的聚合物材料的4D打印

四维 (4D) 打印是一种新兴技术,具有制造复杂、刺激响应性 3D 结构的巨大能力,为组织和器官工程应用提供了巨大潜力。尽管4D概念在2013年首次被强调,但广泛的研究迅速发展,对4D的定义也有了更深入的理解和断言。在这篇综述中,我们首先建立 4D 打印的标准,然后对该领域最先进的技术进步进行了广泛的总结。变换预编程 4D 打印和形状记忆聚合物 4D 打印都得到了深入研究。随后我们将探索和讨论4D打印在组织和器官再生中的应用,例如开发合成组织和植入式支架,以及未来的观点和结论。
更新日期:2017-12-01
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