Lactoferrin is a glycoprotein widely present in mammalian secretions and possesses documented protective effects, including antimicrobial and anti-inflammatory properties. While its therapeutic use is being investigated for a myriad of diseases, there is increasing interest in its application for skin disease. Our objective was to systematically review the clinical evidence for the use and efficacy of lactoferrin for the treatment of dermatological conditions. Pubmed and Embase databases were searched for clinical studies evaluating lactoferrin for dermatological conditions. A total of six studies were reviewed. Of the current clinical trials, there is encouraging evidence to suggest that lactoferrin may be beneficial in acne, psoriasis, and diabetic ulcerations. Although the current evidence is promising, further research is necessary to establish lactoferrin as complementary therapy in the clinical setting.

乳铁蛋白是一种广泛存在于哺乳动物分泌物中的糖蛋白，并具有记录的保护作用，包括抗微生物和抗炎特性。尽管人们正在研究其在多种疾病中的治疗用途，但其在皮肤疾病中的应用越来越引起人们的兴趣。我们的目标是系统地回顾乳铁蛋白在皮肤病学治疗中的用途和功效的临床证据。搜索Pubmed和Embase数据库以获得评估乳铁蛋白皮肤病学状况的临床研究。总共审查了六项研究。在当前的临床试验中，有令人鼓舞的证据表明，乳铁蛋白可能对痤疮，牛皮癣和糖尿病性溃疡有益。尽管目前的证据是有希望的，