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The added value of small-molecule chirality in technological applications
Nature Reviews Chemistry ( IF 36.3 ) Pub Date : 2017-06-07 , DOI: 10.1038/s41570-017-0045
Jochen R. Brandt , Francesco Salerno , Matthew J. Fuchter

Chirality is a fundamental symmetry property; chiral objects, such as chiral small molecules, exist as a pair of non-superimposable mirror images. Although small-molecule chirality is routinely considered in biologically focused application areas (such as drug discovery and chemical biology), other areas of scientific development have not considered small-molecule chirality to be central to their approach. In this Review, we highlight recent research in which chirality has enabled advancement in technological applications. We showcase examples in which the presence of small-molecule chirality is exploited in ways beyond the simple interaction of two different chiral molecules; this can enable the detection and emission of chiral light, help to control molecular motion, or provide a means to control electron spin and bulk charge transport. Thus, we demonstrate that small-molecule chirality is a highly promising avenue for a wide range of technologically oriented scientific endeavours.



中文翻译:

小分子手性在技术应用中的附加值

手性是基本的对称性质。手性对象(例如手性小分子)以一对不可重叠的镜像存在。尽管在以生物学为重点的应用领域(例如药物发现和化学生物学)中通常考虑使用小分子手性,但科学发展的其他领域并未将小分子手性视为其方法的核心。在本综述中,我们重点介绍了手性在技术应用方面取得了进步的最新研究。我们展示了一些例子,其中利用了小分子手性的存在,而不仅仅是两个不同手性分子的简单相互作用。这可以检测和发射手性光,帮助控制分子运动,或提供控制电子自旋和大量电荷传输的方法。因此,

更新日期:2017-06-17
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