The renaissance in corrole chemistry is strongly correlated with synthetic breakthroughs that started in 1999, regarding the one-pot rather than multistep syntheses of this heme-like N4 macrocycle. This largely improved synthetic accessibility allowed for technological advances wherein the corresponding metal complexes have since been introduced as key elements. Great emphasis was devoted to the elucidation of the unique fundamental features that distinguish corrole ligands, among them outstanding electron donation (σ by the N atoms and π by the macrocycle) to transition metals chelated by them. Such investigations remain crucial for enabling the by-demand tuning of metallocorrole properties for distinctly different applications. These range from the catalysis of organic reactions, through bioimaging and disease prevention/treatment strategies, to photo- and electrocatalysis for clean energy. Surveyed are the original reports that impacted these developments, together with some of the most recent advances.

中文翻译：

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科罗尔科技的里程碑和最新进展

咔咯化学的复兴与 1999 年开始的合成突破密切相关，即这种类血红素 N4 大环化合物的一锅合成而非多步合成。这种大大改进的合成可及性允许技术进步，其中相应的金属配合物已作为关键元素引入。重点致力于阐明区分咔咯配体的独特基本特征，其中包括出色的电子捐赠（N 原子的 σ 和大环的 π）给它们螯合的过渡金属。此类研究对于针对截然不同的应用实现按需调整金属咯特性仍然至关重要。这些范围从有机反应的催化，到生物成像和疾病预防/治疗策略，到用于清洁能源的光催化和电催化。调查的是影响这些发展的原始报告，以及一些最新进展。