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Long non-coding RNA-NONMMMUT004552.2 regulates the unloading-induced bone loss through the miRNA-15b-5p/Syne1 in mice npj Micrograv. (IF 5.1) Pub Date : 2024-03-23 Zheng Zhang, Yu Jing, Ang Zhang, JiShan Liu, Heming Yang, Xiaotong Lou, Liyan Xu, Min Liu, Yikun Zhang, Jianwen Gu
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Cooling of a granular gas mixture in microgravity npj Micrograv. (IF 5.1) Pub Date : 2024-03-22 Dmitry Puzyrev, Torsten Trittel, Kirsten Harth, Ralf Stannarius
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Cellular mechanotransduction of human osteoblasts in microgravity npj Micrograv. (IF 5.1) Pub Date : 2024-03-21 Nadab H. Wubshet, Grace Cai, Samuel J. Chen, Molly Sullivan, Mark Reeves, David Mays, Morgan Harrison, Paul Varnado, Benjamin Yang, Esmeralda Arreguin-Martinez, Yunjia Qu, Shan-Shan Lin, Pamela Duran, Carlos Aguilar, Shelby Giza, Twyman Clements, Allen P. Liu
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Cryogenic propellant management in space: open challenges and perspectives npj Micrograv. (IF 5.1) Pub Date : 2024-03-20 Alessia Simonini, Michael Dreyer, Annafederica Urbano, Francesco Sanfedino, Takehiro Himeno, Philipp Behruzi, Marc Avila, Jorge Pinho, Laura Peveroni, Jean-Baptiste Gouriet
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Levels of evidence for human system risk evaluation npj Micrograv. (IF 5.1) Pub Date : 2024-03-20 Jessica Ward, Robert J. Reynolds, Erin Connell, Wilma Anton, Avalon Kabeel, Jacqueline M. Charvat, Nicholas Nartey, Kristina Marotta, Ahmed Abukmail, Dan M. Buckland, Mary Van Baalen, Erik Antonsen
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Causal diagramming for assessing human system risk in spaceflight npj Micrograv. (IF 5.1) Pub Date : 2024-03-19 Erik Antonsen, Robert J. Reynolds, Jacqueline Charvat, Erin Connell, Avalon Monti, Devan Petersen, Nicholas Nartey, Wilma Anton, Ahmed Abukmail, Kristina Marotta, Mary Van Baalen, Daniel M. Buckland
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Autophagy formation, microtubule disorientation, and alteration of ATG8 and tubulin gene expression under simulated microgravity in Arabidopsis thaliana npj Micrograv. (IF 5.1) Pub Date : 2024-03-18 Alla Yemets, Ruslana Shadrina, Rostyslav Blume, Svitlana Plokhovska, Yaroslav Blume
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Future opportunities in solar system plasma science through ESA’s exploration programme npj Micrograv. (IF 5.1) Pub Date : 2024-03-14 Mats Holmstrom, Mark Lester, Beatriz Sanchez-Cano
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Enhanced assembly of bacteriophage T7 produced in cell-free reactions under simulated microgravity npj Micrograv. (IF 5.1) Pub Date : 2024-03-15 François-Xavier Lehr, Bruno Pavletić, Timo Glatter, Thomas Heimerl, Ralf Moeller, Henrike Niederholtmeyer
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The effects of long-term exposure to microgravity and body orientation relative to gravity on perceived traveled distance npj Micrograv. (IF 5.1) Pub Date : 2024-03-13 Björn Jörges, Nils Bury, Meaghan McManus, Ambika Bansal, Robert S. Allison, Michael Jenkin, Laurence R. Harris
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Daily artificial gravity partially mitigates vestibular processing changes associated with head-down tilt bedrest npj Micrograv. (IF 5.1) Pub Date : 2024-03-12 G. D. Tays, K. E. Hupfeld, H. R. McGregor, N. E. Beltran, Y. E. De Dios, E. Mulder, J. J. Bloomberg, A. P. Mulavara, S. J. Wood, R. D. Seidler
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Microgravity effects on nonequilibrium melt processing of neodymium titanate: thermophysical properties, atomic structure, glass formation and crystallization npj Micrograv. (IF 5.1) Pub Date : 2024-03-06 Stephen K. Wilke, Abdulrahman Al-Rubkhi, Chihiro Koyama, Takehiko Ishikawa, Hirohisa Oda, Brian Topper, Elizabeth M. Tsekrekas, Doris Möncke, Oliver L. G. Alderman, Vrishank Menon, Jared Rafferty, Emma Clark, Alan L. Kastengren, Chris J. Benmore, Jan Ilavsky, Jörg Neuefeind, Shinji Kohara, Michael SanSoucie, Brandon Phillips, Richard Weber
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Acute and short-term fluctuations in gravity are associated with changes in circulatory plasma protein levels npj Micrograv. (IF 5.1) Pub Date : 2024-03-04 Alexander Lang, Stephan Binneboessel, Fabian Nienhaus, Raphael Romano Bruno, Georg Wolff, Kerstin Piayda, Susanne Pfeiler, Hakima Ezzahoini, Daniel Oehler, Malte Kelm, Holger Winkels, Norbert Gerdes, Christian Jung
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Dynamic changes in perivascular space morphology predict signs of spaceflight-associated neuro-ocular syndrome in bed rest npj Micrograv. (IF 5.1) Pub Date : 2024-03-01 Sutton B. Richmond, Rachael D. Seidler, Jeffrey J. Iliff, Daniel L. Schwartz, Madison Luther, Lisa C. Silbert, Scott J. Wood, Jacob J. Bloomberg, Edwin Mulder, Jessica K. Lee, Alberto De Luca, Juan Piantino
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A perspective on the evidence for glymphatic obstruction in spaceflight associated neuro-ocular syndrome and fatigue npj Micrograv. (IF 5.1) Pub Date : 2024-02-28 Grant Alexander Bateman, Alexander Robert Bateman
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Linking cerebral hemodynamics and ocular microgravity-induced alterations through an in silico-in vivo head-down tilt framework npj Micrograv. (IF 5.1) Pub Date : 2024-02-27 Matteo Fois, Ana Diaz-Artiles, Syeda Yasmin Zaman, Luca Ridolfi, Stefania Scarsoglio
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Versatile spaceborne photonics with chalcogenide phase-change materials npj Micrograv. (IF 5.1) Pub Date : 2024-02-20 Hyun Jung Kim, Matthew Julian, Calum Williams, David Bombara, Juejun Hu, Tian Gu, Kiumars Aryana, Godfrey Sauti, William Humphreys
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Effects of total sleep deprivation on performance in a manual spacecraft docking task npj Micrograv. (IF 5.1) Pub Date : 2024-02-21 Sarah Piechowski, Lennard J. Kalkoffen, Sibylle Benderoth, Oliver T. Wolf, Jörn Rittweger, Daniel Aeschbach, Christian Mühl
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Flight test results for microgravity active vibration isolation system on-board Chinese Space Station npj Micrograv. (IF 5.1) Pub Date : 2024-02-19 Wei Liu, Yang Gao, Long Zhang, Tianji Zou, Mengxi Yu, Tuo Zheng
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Simulated microgravity attenuates myogenesis and contractile function of 3D engineered skeletal muscle tissues npj Micrograv. (IF 5.1) Pub Date : 2024-02-16 Zhanping Ren, Eun Hyun Ahn, Minjae Do, Devin B. Mair, Amir Monemianesfahani, Peter H. U. Lee, Deok-Ho Kim
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How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms? npj Micrograv. (IF 5.1) Pub Date : 2024-02-10 Trent Davis, Kevin Tabury, Shouan Zhu, Debora Angeloni, Sarah Baatout, Alexandra Benchoua, Juergen Bereiter-Hahn, Daniele Bottai, Judith-Irina Buchheim, Marco Calvaruso, Eugénie Carnero-Diaz, Sara Castiglioni, Duccio Cavalieri, Gabriele Ceccarelli, Alexander Choukér, Francesca Cialdai, Gianni Ciofani, Giuseppe Coppola, Gabriella Cusella, Andrea Degl’Innocenti, Jean-Francois Desaphy, Jean-Pol Frippiat
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Systematic review of the use of ultrasound for venous assessment and venous thrombosis screening in spaceflight npj Micrograv. (IF 5.1) Pub Date : 2024-02-05 Antoine Elias, Tobias Weber, David A. Green, Katie M. Harris, Jonathan M. Laws, Danielle K. Greaves, David S. Kim, Lucia Mazzolai-Duchosal, Lara Roberts, Lonnie G. Petersen, Ulrich Limper, Andrej Bergauer, Michael Elias, Andrew Winnard, Nandu Goswami
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Influence of microgravity on spontaneous calcium activity of primary hippocampal neurons grown in microfluidic chips npj Micrograv. (IF 5.1) Pub Date : 2024-02-06 Pierre-Ewen Lecoq, Chloé Dupuis, Xavier Mousset, Xavier Benoit-Gonnin, Jean-Michel Peyrin, Jean-Luc Aider
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Bubble nucleation and growth on microstructured surfaces under microgravity npj Micrograv. (IF 5.1) Pub Date : 2024-01-30 Qiushi Zhang, Dongchuan Mo, Seunghyun Moon, Jiya Janowitz, Dan Ringle, David Mays, Andrew Diddle, Jason Rexroat, Eungkyu Lee, Tengfei Luo
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Domains of life sciences in spacefaring: what, where, and how to get involved npj Micrograv. (IF 5.1) Pub Date : 2024-01-29 Aaron J. Berliner, Spencer Zezulka, Gwyneth A. Hutchinson, Sophia Bertoldo, Charles S. Cockell, Adam P. Arkin
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Unlocking the potential: analyzing 3D microstructure of small-scale cement samples from space using deep learning npj Micrograv. (IF 5.1) Pub Date : 2024-01-25 Vishnu Saseendran, Namiko Yamamoto, Peter J. Collins, Aleksandra Radlińska, Sara Mueller, Enrique M. Jackson
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The effect of space travel on human reproductive health: a systematic review npj Micrograv. (IF 5.1) Pub Date : 2024-01-18 Marta Gimunová, Ana Carolina Paludo, Martina Bernaciková, Julie Bienertova-Vasku
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Quantitative ultrasound image assessment of the optic nerve subarachnoid space during 90-day head-down tilt bed rest npj Micrograv. (IF 5.1) Pub Date : 2024-01-17 Yuan Xie, Yingdi Fu, Yaqi Shao, Lina Qu, Jiangang Yang, Chengjia Yang, Kun Zhou, Kai Li, Zi Xu, Dong Xu, Kai Cao, Ning Tian, Ke Lv, Linjie Wang, Yaping Wang, Ningli Wang, Yinghui Li
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Morphologic and genomic changes of thyroid cancer cell lines exposed to conditions of simulated microgravity npj Micrograv. (IF 5.1) Pub Date : 2024-01-15 Jong-hyuk Ahn, Sungyeon Park, Young Mi Hwang, Yun Suk Choi, Jin Wook Yi
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Changes in real-world walking speed following 60-day bed-rest npj Micrograv. (IF 5.1) Pub Date : 2024-01-13 Marcello Grassi, Fiona Von Der Straten, Charlotte Pearce, Jessica Lee, Marcin Mider, Uwe Mittag, Wolfram Sies, Edwin Mulder, Martin Daumer, Jörn Rittweger
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Modelling large scale artery haemodynamics from the heart to the eye in response to simulated microgravity npj Micrograv. (IF 5.1) Pub Date : 2024-01-13 Harrison T. Caddy, Lachlan J. Kelsey, Louis P. Parker, Daniel J. Green, Barry J. Doyle
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Neuro-ophthalmological changes in healthy females exposed to a 5-day dry immersion: a pilot study npj Micrograv. (IF 5.1) Pub Date : 2024-01-11 Marc Kermorgant, Thibault Chedmail, Fanny Varenne, Marie-Pierre Bareille, Arnaud Beck, Rebecca Billette de Villemeur, Pierre Fournié, Lisa Grondin, Ophélie Hélissen, Charlotte Membrives, Nathalie Nasr, Anne Pavy-Le Traon, Vincent Soler
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Sensorimotor adaptation of locomotor synergies to gravitational constraint npj Micrograv. (IF 5.1) Pub Date : 2024-01-11 Etienne Guillaud, Vincent Leconte, Emilie Doat, Dominique Guehl, Jean-René Cazalets
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Whole transcriptome analysis highlights nutrient limitation of nitrogen cycle bacteria in simulated microgravity npj Micrograv. (IF 5.1) Pub Date : 2024-01-10 Tom Verbeelen, Celia Alvarez Fernandez, Thanh Huy Nguyen, Surya Gupta, Raf Aarts, Kevin Tabury, Baptiste Leroy, Ruddy Wattiez, Siegfried E. Vlaeminck, Natalie Leys, Ramon Ganigué, Felice Mastroleo
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Altered quorum sensing and physiology of Staphylococcus aureus during spaceflight detected by multi-omics data analysis npj Micrograv. (IF 5.1) Pub Date : 2024-01-08 Matthew R. Hauserman, Mariola J. Ferraro, Ronan K. Carroll, Kelly C. Rice
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Ocular complaints and diagnoses in spaceflight npj Micrograv. (IF 5.1) Pub Date : 2024-01-02 Elana Meer, Seanna R. Grob, Kris Lehnhardt, Aenor Sawyer
The NASA human system risk board (HSRB) has long focused on trauma and acute medical illness as a key contributor to high level in-flight medical risk. However, ocular issues, trauma, and complaints during spaceflight are poorly characterized. In a retrospective case series, the NASA data from the life sciences data archieve (LSDA) and the lifetime surveillance of astronaught health (LSAH) was queried
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Transcriptomic dynamics in the transition from ground to space are revealed by Virgin Galactic human-tended suborbital spaceflight npj Micrograv. (IF 5.1) Pub Date : 2023-12-20 Robert J. Ferl, Mingqi Zhou, Hunter F. Strickland, Natasha J. Haveman, Jordan B. Callaham, Sirisha Bandla, Daniel Ambriz, Anna-Lisa Paul
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Effectiveness of caffeine and blue-enriched light on cognitive performance and electroencephalography correlates of alertness in a spaceflight robotics simulation npj Micrograv. (IF 5.1) Pub Date : 2023-12-19 Erin E. Flynn-Evans, Melanie Rueger, Andrew M. Liu, Raquel C. Galvan-Garza, Alan Natapoff, Charles M. Oman, Steven W. Lockley
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Effects of caffeine and blue-enriched light on spare visual attention during simulated space teleoperation npj Micrograv. (IF 5.1) Pub Date : 2023-12-19 Andrew M. Liu, Raquel C. Galvan-Garza, Erin E. Flynn-Evans, Melanie Rueger, Alan Natapoff, Steven W. Lockley, Charles M. Oman
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Behavior of glioblastoma brain tumor stem cells following a suborbital rocket flight: reaching the “edge” of outer space npj Micrograv. (IF 5.1) Pub Date : 2023-12-18 Cesar A. Garcia, Paola Suárez-Meade, Mieu Brooks, Adip G. Bhargav, Michelle L. Freeman, Lawrence M. Harvey, John Quinn, Alfredo Quiñones-Hinojosa
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Microgravity triggers ferroptosis and accelerates senescence in the MG-63 cell model of osteoblastic cells npj Micrograv. (IF 5.1) Pub Date : 2023-12-16 Nancy Garbacki, Jérôme Willems, Thibaut Neutelings, Charles Lambert, Christophe Deroanne, Astrid Adrian, Markus Franz, Matthias Maurer, Philippe De Gieter, Betty Nusgens, Alain Colige
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Explainable machine learning identifies multi-omics signatures of muscle response to spaceflight in mice npj Micrograv. (IF 5.1) Pub Date : 2023-12-13 Kevin Li, Riya Desai, Ryan T. Scott, Joel Ricky Steele, Meera Machado, Samuel Demharter, Adrienne Hoarfrost, Jessica L. Braun, Val A. Fajardo, Lauren M. Sanders, Sylvain V. Costes
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Unraveling the intricate connection between dietary factors and the success in long-term space missions npj Micrograv. (IF 5.1) Pub Date : 2023-12-13 Paola Pittia, Stéphane Blanc, Martina Heer
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Space microgravity increases expression of genes associated with proliferation and differentiation in human cardiac spheres npj Micrograv. (IF 5.1) Pub Date : 2023-12-09 Hyun Hwang, Antonio Rampoldi, Parvin Forghani, Dong Li, Jordan Fite, Gene Boland, Kevin Maher, Chunhui Xu
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Effects of whole-body vibration or resistive-vibration exercise on blood clotting and related biomarkers: a systematic review npj Micrograv. (IF 5.1) Pub Date : 2023-12-06 Lucrezia Zuccarelli, Giovanni Baldassarre, Andrew Winnard, Katie M. Harris, Tobias Weber, David A. Green, Lonnie G. Petersen, Tovy Haber Kamine, Lara Roberts, David S. Kim, Danielle K. Greaves, Roopen Arya, Jonathan M. Laws, Antoine Elias, Jörn Rittweger, Bruno Grassi, Nandu Goswami
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Genetic diversity modulates the physical and transcriptomic response of skeletal muscle to simulated microgravity in male mice npj Micrograv. (IF 5.1) Pub Date : 2023-12-01 Yasmina Zeineddine, Michael A. Friedman, Evan G. Buettmann, Lovell B. Abraham, Gabriel A. Hoppock, Henry J. Donahue
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Medical ethics of long-duration spaceflight npj Micrograv. (IF 5.1) Pub Date : 2023-11-28 Siddharth Rajput, Ivy Mayor, Madison Diamond, Mark Rosenberg, Victor Cole, Nikita Bhakare, Omar Aziz, Anderson L. Wilder
With the advent of novel and emerging technologies, long duration spaceflight will become more common; along with it, an increase in its inherent health risks. However, health-related ethical issues arising during long-duration spaceflight remain poorly characterized, uncertain and unpredictable. Medical ethics is defined as a set of moral principles, beliefs and values that guides choices about medical
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How do gravity alterations affect animal and human systems at a cellular/tissue level? npj Micrograv. (IF 5.1) Pub Date : 2023-10-21 Francesca Cialdai, Austin M. Brown, Cory W. Baumann, Debora Angeloni, Sarah Baatout, Alexandra Benchoua, Juergen Bereiter-Hahn, Daniele Bottai, Judith-Irina Buchheim, Marco Calvaruso, Eugénie Carnero-Diaz, Sara Castiglioni, Duccio Cavalieri, Gabriele Ceccarelli, Alexander Choukér, Gianni Ciofani, Giuseppe Coppola, Gabriella Cusella, Andrea Degl’Innocenti, Jean-Francois Desaphy, Jean-Pol Frippiat, Michael
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Microgravity studies of solidification patterns in model transparent alloys onboard the International Space Station npj Micrograv. (IF 5.1) Pub Date : 2023-10-18 S. Akamatsu, S. Bottin-Rousseau, V. T. Witusiewicz, U. Hecht, M. Plapp, A. Ludwig, J. Mogeritsch, M. Şerefoğlu, N. Bergeon, F. L. Mota, L. Sturz, G. Zimmermann, S. McFadden, W. Sillekens
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Simplified equations for object trajectories in rotating space habitats and space juggling npj Micrograv. (IF 5.1) Pub Date : 2023-10-12 R. Adam Dipert
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Additive manufacturing of metallic glass from powder in space npj Micrograv. (IF 5.1) Pub Date : 2023-10-06 Christian Neumann, Johannes Thore, Mélanie Clozel, Jens Günster, Janka Wilbig, Andreas Meyer
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An airlock concept to reduce contamination risks during the human exploration of Mars npj Micrograv. (IF 5.1) Pub Date : 2023-10-07 Daniel Vrankar, Cyprien Verseux, Christiane Heinicke
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Bisphosphonate conjugation enhances the bone-specificity of NELL-1-based systemic therapy for spaceflight-induced bone loss in mice npj Micrograv. (IF 5.1) Pub Date : 2023-09-18 Pin Ha, Jin Hee Kwak, Yulong Zhang, Jiayu Shi, Luan Tran, Timothy Pan Liu, Hsin-Chuan Pan, Samantha Lee, Jong Kil Kim, Eric Chen, Yasaman Shirazi-Fard, Louis S. Stodieck, Andy Lin, Zhong Zheng, Stella Nuo Dong, Xinli Zhang, Benjamin M. Wu, Kang Ting, Chia Soo
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Theoretical design of a space bioprocessing system to produce recombinant proteins npj Micrograv. (IF 5.1) Pub Date : 2023-09-16 Mathangi Soundararajan, Matthew B. Paddock, Michael Dougherty, Harry W. Jones, John A. Hogan, Frances M. Donovan, Jonathan M. Galazka, A. Mark Settles
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Human skeletal muscle tissue chip autonomous payload reveals changes in fiber type and metabolic gene expression due to spaceflight npj Micrograv. (IF 5.1) Pub Date : 2023-09-15 Maddalena Parafati, Shelby Giza, Tushar S. Shenoy, Jorge A. Mojica-Santiago, Meghan Hopf, Legrand K. Malany, Don Platt, Isabel Moore, Zachary A. Jacobs, Paul Kuehl, Jason Rexroat, Gentry Barnett, Christine E. Schmidt, William T. McLamb, Twyman Clements, Paul M. Coen, Siobhan Malany
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Impacts of radiation exposure, hindlimb unloading, and recovery on murine skeletal muscle cell telomere length npj Micrograv. (IF 5.1) Pub Date : 2023-09-15 Elisia D. Tichy, Ji-Hyung Lee, Grant Li, Katrina N. Estep, F. Brad Johnson, Foteini Mourkioti
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Fluidic shaping and in-situ measurement of liquid lenses in microgravity npj Micrograv. (IF 5.1) Pub Date : 2023-09-11 Omer Luria, Mor Elgarisi, Valeri Frumkin, Alexey Razin, Jonathan Ericson, Khaled Gommed, Daniel Widerker, Israel Gabay, Ruslan Belikov, Jay Bookbinder, Edward Balaban, Moran Bercovici
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Evaluation of free-floating tracheal intubation in weightlessness via ice-pick position with a direct laryngoscopy and classic approach with indirect videolaryngoscopy npj Micrograv. (IF 5.1) Pub Date : 2023-09-08 Séamus Thierry, François Jaulin, Clément Starck, Philippe Ariès, Jan Schmitz, Steffen Kerkhoff, Cécile Isabelle Bernard, Matthieu Komorowski, Tobias Warnecke, Jochen Hinkelbein
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Microgravity and evasion of plant innate immunity by human bacterial pathogens npj Micrograv. (IF 5.1) Pub Date : 2023-09-07 Noah Totsline, Kalmia E. Kniel, Harsh P. Bais
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Updates to the NASA human system risk management process for space exploration npj Micrograv. (IF 5.1) Pub Date : 2023-09-07 Erik L. Antonsen, Erin Connell, Wilma Anton, Robert J. Reynolds, Daniel M. Buckland, Mary Van Baalen