-
Drug testing of monodisperse arrays of live microdissected tumors using a valved multiwell microfluidic platform Lab Chip (IF 6.1) Pub Date : 2024-04-23 Ethan J. Lockhart, Lisa F. Horowitz, Adán Rodríguez, Songli Zhu, Tran Nguyen, Mehdi Mehrabi, Taranjit S. Gujral, Albert Folch
-
Correction: Direct laser writing-enabled 3D printing strategies for microfluidic applications Lab Chip (IF 6.1) Pub Date : 2024-04-22 Olivia M. Young, Xin Xu, Sunandita Sarker, Ryan D. Sochol
Correction for ‘Direct laser writing-enabled 3D printing strategies for microfluidic applications’ by Olivia M. Young et al., Lab Chip, 2024, DOI: https://doi.org/10.1039/D3LC00743J.
-
Microflow sensing and control using an in-channel birefringent biomembrane Lab Chip (IF 6.1) Pub Date : 2024-04-19 Nan Jia, Tianyang Deng, Charles Larouche, Tigran Galstian, André Bégin-Drolet, Jesse Greener
-
Rocking- and diffusion-based culture of tumor spheroids-on-a-chip Lab Chip (IF 6.1) Pub Date : 2024-04-15 Duomei Tian, Zheng Mao, Li Wang, Xiaochen Huang, Wei Wang, Haoyue Luo, Juan Peng, Yong Chen
-
Development of a microfluidic device to enrich and detect zearalenone in food using quantum dot-embedded molecularly imprinted polymers Lab Chip (IF 6.1) Pub Date : 2024-04-17 Marti Z. Hua, Shenmiao Li, M. S. Roopesh, Xiaonan Lu
-
Portable platform for leukocyte extraction from blood using sheath-free microfluidic DLD Lab Chip (IF 6.1) Pub Date : 2024-04-15 Oriana G. Chavez-Pineda, Roberto Rodriguez-Moncayo, Alan M. Gonzalez-Suarez, Pablo E. Guevara-Pantoja, Jose L. Maravillas-Montero, Jose L. Garcia-Cordero
-
A paper-based dual functional biosensor for safe and user-friendly point-of-care urine analysis Lab Chip (IF 6.1) Pub Date : 2024-04-12 Yujia Li, Yingqi Kong, Yubing Hu, Yixuan Li, Rica Asrosa, Wenyu Zhang, Buddha Deka Boruah, Ali K. Yetisen, Andrew Davenport, Tung-Chun Lee, Bing Li
-
Versatile hybrid technique for passive straight micromixer manufacturing by combining pulsed laser ablation, stereolithographic 3D printing and computational fluid dynamics Lab Chip (IF 6.1) Pub Date : 2024-04-11 Bastián Carnero, Yago Radziunas-Salinas, Bruno K. Rodiño-Janeiro, Sylvana Varela Ballesta, M. Teresa Flores-Arias
-
A point-of-care testing platform for on-site identification of genetically modified crops Lab Chip (IF 6.1) Pub Date : 2024-04-10 Yangyang Wang, Furui Yang, Yingyi Fu, Xin He, Haowei Tian, Lili Yang, Mengxi Wu, Jijuan Cao, Junshan Liu
-
Dielectrophoretic characterization and selection of non-spherical flagellate algae in parallel channels with right-angle bipolar electrodes Lab Chip (IF 6.1) Pub Date : 2024-04-08 Xiaoming Chen, Shun Liu, Mo Shen, Jishun Shi, Chungang Wu, Zhipeng Song, Yong Zhao
-
Spatially controlled diffusion range of tumor-associated angiogenic factors to develop a tumor model using a microfluidic resistive circuit Lab Chip (IF 6.1) Pub Date : 2024-04-05 Yu-Hsiang Hsu, Wen-Chih Yang, Yi-Ting Chen, Che-Yu Lin, Chiou-Fong Yang, Wei-Wen Liu, Subhashree Shivani, Pai-Chi Li
Developing a tumor model with vessels has been a challenge in microfluidics. This difficulty is because cancer cells can overgrow in a co-culture system. The up-regulation of anti-angiogenic factors during the initial tumor development can hinder neovascularization. The standard method is to develop a quiescent vessel network before loading a tumor construct in an adjacent chamber, which simulates
-
Direct laser writing-enabled 3D printing strategies for microfluidic applications Lab Chip (IF 6.1) Pub Date : 2024-04-04 Olivia M. Young, Xin Xu, Sunandita Sarker, Ryan D. Sochol
Over the past decade, additive manufacturing—or “three-dimensional (3D) printing”—has attracted increasing attention in the Lab on a Chip community as a pathway to achieve sophisticated system architectures that are difficult or infeasible to fabricate via conventional means. One particularly promising 3D manufacturing technology is “direct laser writing (DLW)”, which leverages two-photon (or multi-photon)
-
Piezoelectric and microfluidic tuning of an infrared cavity for vibrational polariton studies Lab Chip (IF 6.1) Pub Date : 2024-04-05 Wei Wang, Jaime de la Fuente Diez, Nicolas Delsuc, Juan Peng, Riccardo Spezia, Rodolphe Vuilleumier, Yong Chen
-
Study on the hemodynamic effects of different pulsatile working modes of a rotary blood pump using a microfluidic platform that realizes in vitro cell culture effectively Lab Chip (IF 6.1) Pub Date : 2024-04-05 Lixue Liang, Xueying Wang, Dong Chen, Palaniappan Sethu, Guruprasad A. Giridharan, Yanxia Wang, Yu Wang, Kai-Rong Qin
-
A microfluidic-based gut-on-a-chip model containing the gut microbiota of patients with depression reveals physiological characteristics similar to depression Lab Chip (IF 6.1) Pub Date : 2024-04-04 Wenxin Wang, Yiyuan Liu, Zhikai Yao, Dengbo Chen, Yue Tang, Jingwei Cui, Jiangjiang Zhang, Hong Liu, Zikai Hao
-
High-throughput viscoelastic characterization of cells in hyperbolic microchannels Lab Chip (IF 6.1) Pub Date : 2024-04-03 Felix Reichel, Ruchi Goswami, Salvatore Girardo, Jochen Guck
-
Evaluating thrombosis risk and patient-specific treatment strategy using an atherothrombosis-on-chip model Lab Chip (IF 6.1) Pub Date : 2024-04-02 Fahima Akther, Hedieh Fallahi, Jun Zhang, Nam-Trung Nguyen, Hang Thu Ta
-
Integrated high performance microfluidic organic analysis instrument for planetary and space exploration Lab Chip (IF 6.1) Pub Date : 2024-04-02 Anna L. Butterworth, Matin Golozar, Zachary Estlack, Jeremy McCauley, Richard A. Mathies, Jungkyu Kim
-
Investigation of air bubble behaviour after gas embolism events induced in a microfluidic network mimicking microvasculature Lab Chip (IF 6.1) Pub Date : 2024-04-01 Mohammad Mahdi Mardanpour, Ayyappasamy Sudalaiyadum Perumal, Zahra Mahmoodi, Karine Baassiri, Gala Montiel-Rubies, Kenneth M. LeDez, Dan V. Nicolau
-
Development of a self-contained microfluidic chip and an internet-of-things-based point-of-care device for automated identification of respiratory viruses Lab Chip (IF 6.1) Pub Date : 2024-03-28 Huynh Quoc Nguyen, Van Dan Nguyen, Vu Minh Phan, Tae Seok Seo
-
Vascularized tissue on mesh-assisted platform (VT-MAP): a novel approach for diverse organoid size culture and tailored cancer drug response analysis Lab Chip (IF 6.1) Pub Date : 2024-03-27 Jungseub Lee, Sangmin Jung, Hye Kyoung Hong, Hyeonsu Jo, Stephen Rhee, Ye-Lin Jeong, Jihoon Ko, Yong Beom Cho, Noo Li Jeon
-
A novel ratiometric design of microfluidic paper-based analytical device for the simultaneous detection of Cu2+ and Fe3+ in drinking water using a fluorescent MOF@tetracycline nanocomposite Lab Chip (IF 6.1) Pub Date : 2024-03-26 Sabah H. Al-Jaf, Sameera Sh. Mohammed Ameen, Khalid M. Omer
-
Brachytherapy on-a-chip: a clinically-relevant approach for radiotherapy testing in 3d biology Lab Chip (IF 6.1) Pub Date : 2024-03-27 Rodin Chermat, Elena Refet-Mollof, Yuji Kamio, Jean-François Carrier, Philip Wong, Thomas Gervais
We describe the first microfluidic device for in vitro testing of brachytherapy (BT), with applications in translational cancer research. Our PDMS-made BT-on-chip system allows highly precise manual insertion of clinical BT seeds, reliable dose calculation using standard clinically-used TG-43 formalism and easy culture of naturally hypoxic spheroids in less than 3 days, thereby increasing the translational
-
Development of wafer-scale multifunctional nanophotonic neural probes for brain activity mapping Lab Chip (IF 6.1) Pub Date : 2024-03-26 Fu Der Chen, Ankita Sharma, David A. Roszko, Tianyuan Xue, Xin Mu, Xianshu Luo, Hongyao Chua, Patrick Guo-Qiang Lo, Wesley D. Sacher, Joyce K. S. Poon
-
Acoustic modulation and non-contact atomization of droplets based on the Fabry–Pérot resonator Lab Chip (IF 6.1) Pub Date : 2024-03-25 Jingjun Li, Xiukun Wang, Fan Yang, Yadong Sun, Lei Zhang
-
A self-assembly and cellular migration based fabrication of high-density 3D tubular constructs of barrier forming membranes Lab Chip (IF 6.1) Pub Date : 2024-03-25 Seyedaydin Jalali, Ponnambalam Ravi Selvaganapathy
Three-dimensional (3D) in vitro models, superior in simulating physiological conditions compared to 2D models, offer intricate cell–cell and cell–ECM interactions with diverse signaling cues like fluid shear stress and growth factor gradients. Yet, developing 3D tissue barrier models, specifically perfusable luminal structures with dense, multicellular constructs maintained for extended durations with
-
Designing and prototyping a novel biosensor based on a volumetric bar-chart chip for urea detection Lab Chip (IF 6.1) Pub Date : 2024-03-22 Mahdi Samadi Khezri, Mohammad Reza Housaindokht, Mojtaba Firouzi
-
A surface-engineered contact lens for tear fluid biomolecule sensing Lab Chip (IF 6.1) Pub Date : 2024-03-22 Aravind M, Sajan D. George
The eyes provide rich physiological information and offer diagnostic potential as a sensing site, and probing tear constituents via the wearable contact lens could be explored for healthcare monitoring. Herein, we propose a novel adhesive contrast contact lens platform that can split tear film by natural means of tear secretion and blinking. The adhesive contrast is realized by selective grafting of
-
Opto-combinatorial indexing enables high-content transcriptomics by linking cell images and transcriptomes Lab Chip (IF 6.1) Pub Date : 2024-03-20 Arata Tsuchida, Taikopaul Kaneko, Kaori Nishikawa, Mayu Kawasaki, Ryuji Yokokawa, Hirofumi Shintaku
-
A microfluidic model to study the effects of arrhythmic flows on endothelial cells Lab Chip (IF 6.1) Pub Date : 2024-03-21 Austin Lai, Adam Hawke, Mokhaled Mohammed, Peter Thurgood, Gianmarco Concilia, Karlheinz Peter, Khashayar Khoshmanesh, Sara Baratchi
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and an important contributor to morbidity and mortality. Endothelial dysfunction has been postulated to be an important contributing factor in cardiovascular events in patients with AF. However, how vascular endothelial cells respond to arrhythmic flow is not fully understood, mainly due to the limitation of current in vitro systems
-
A cheaper substitute for HRP: ultra-small Cu–Au bimetallic enzyme mimics with infinitesimal steric hindrance to promote catalytic lateral flow immunodetection of clenbuterol Lab Chip (IF 6.1) Pub Date : 2024-03-20 Huilan Hu, Jiaqi Tian, Rui Shu, Huihui Liu, Shaochi Wang, Xuechi Yin, Jianlong Wang, Daohong Zhang
-
Correction: Integrated biosensors for monitoring microphysiological systems Lab Chip (IF 6.1) Pub Date : 2024-03-19 Lei Mou, Kalpana Mandal, Marvin Magan Mecwan, Ana Lopez Hernandez, Surjendu Maity, Saurabh Sharma, Rondinelli Donizetti Herculano, Satoru Kawakita, Vadim Jucaud, Mehmet Remzi Dokmeci, Ali Khademhosseini
Correction for ‘Integrated biosensors for monitoring microphysiological systems’ by Lei Mou et al., Lab Chip, 2022, 22, 3801–3816, https://doi.org/10.1039/D2LC00262K.
-
Effect of in-plane and out-of-plane bifurcated microfluidic channels on the flow of aggregating red blood cells Lab Chip (IF 6.1) Pub Date : 2024-03-18 Amirreza Gholivand, Olivera Korculanin, Knut Dahlhoff, Mehrnaz Babaki, Timo Dickscheid, Minne Paul Lettinga
-
Actuation for flexible and stretchable microdevices Lab Chip (IF 6.1) Pub Date : 2024-03-14 Uditha Roshan, Amith Mudugamuwa, Haotian Cha, Samith Hettiarachchi, Jun Zhang, Nam-Trung Nguyen
-
Integrated biocompatible 3D printed isoporous membranes with 7 μm pores Lab Chip (IF 6.1) Pub Date : 2024-03-14 Matthew S. Viglione, Aubrianna Saxton, Dawson Downs, Adam T. Woolley, Kenneth A. Christensen, Pam M. Van Ry, Gregory P. Nordin
-
Distance-based paper analytical device for multiplexed quantification of cytokine biomarkers using carbon dots integrated with molecularly imprinted polymer Lab Chip (IF 6.1) Pub Date : 2024-03-12 Kawin Khachornsakkul, Ruben Del-Rio-Ruiz, Lita Chheang, Wenxin Zeng, Sameer Sonkusale
-
High-throughput 3D microfluidic chip for generation of concentration gradients and mixture combinations Lab Chip (IF 6.1) Pub Date : 2024-03-12 Mingwei Zhao, Jing Yang, Zhenqing Li, Yuan Zeng, Chunxian Tao, Bo Dai, Dawei Zhang, Yoshinori Yamaguchi
-
Deep learning-enabled detection of rare circulating tumor cell clusters in whole blood using label-free, flow cytometry Lab Chip (IF 6.1) Pub Date : 2024-03-08 Nilay Vora, Prashant Shekar, Taras Hanulia, Michael Esmail, Abani Patra, Irene Georgakoudi
-
Synthesis and photocatalytic property of Au–TiO2 nanocomposites with controlled morphologies in microfluidic chips Lab Chip (IF 6.1) Pub Date : 2024-03-07 Ziran Ye, Ping Lu, Yiben Chen, Zhixian Xu, Haixia Huang, Mingjia Zhi, Zi Ang Chen, Bo Yan
-
Tuneable hydrogel patterns in pillarless microfluidic devices Lab Chip (IF 6.1) Pub Date : 2024-03-06 Claudia Olaizola-Rodrigo, Sujey Palma-Florez, Teodora Ranđelović, Clara Bayona, Mehran Ashrafi, Josep Samitier, Anna Lagunas, Mònica Mir, Manuel Doblaré, Ignacio Ochoa, Rosa Monge, Sara Oliván
-
Next generation microfluidics: fulfilling the promise of lab-on-a-chip technologies Lab Chip (IF 6.1) Pub Date : 2024-03-05 Umut A. Gurkan, David K. Wood, Dorn Carranza, Luke H. Herbertson, Scott L. Diamond, E. Du, Suvajyoti Guha, Jorge Di Paola, Patrick C. Hines, Ian Papautsky, Sergey S. Shevkoplyas, Nathan J. Sniadecki, Vamsee K. Pamula, Prithu Sundd, Asif Rizwan, Pankaj Qasba, Wilbur A. Lam
-
Droplet microfluidic system for high throughput and passive selection of bacteria producing biosurfactants Lab Chip (IF 6.1) Pub Date : 2024-03-04 Klaudia Staskiewicz, Maria Dabrowska-Zawada, Lukasz Kozon, Zofia Olszewska, Lukasz Drewniak, Tomasz S. Kaminski
-
Tonicity-induced cargo loading into extracellular vesicles Lab Chip (IF 6.1) Pub Date : 2024-02-28 Chaeeun Lee, Sumit Kumar, Juhee Park, Yongjun Choi, Elizabeth Maria Clarissa, Yoon-Kyoung Cho
-
Recent developments and future perspectives of microfluidics and smart technologies in wearable devices Lab Chip (IF 6.1) Pub Date : 2024-02-28 Sasikala Apoorva, Nam-Trung Nguyen, Kamalalayam Rajan Sreejith
-
Deciphering fibroblast-induced drug resistance in non-small cell lung carcinoma through patient-derived organoids in agarose microwells Lab Chip (IF 6.1) Pub Date : 2024-02-27 Qiyue Luan, Ines Pulido, Angelique Isagirre, Julian Carretero, Jian Zhou, Takeshi Shimamura, Ian Papautsky
-
Polar coordinate active-matrix digital microfluidics for high-resolution concentration gradient generation Lab Chip (IF 6.1) Pub Date : 2024-02-27 Bingbing Zhang, Jinxin Fu, Maohua Du, Kai Jin, Qi Huang, Jiahao Li, Dongping Wang, Siyi Hu, Jinhua Li, Hanbin Ma
-
Microphysiological pancreas-on-chip platform with integrated sensors to model endocrine function and metabolism Lab Chip (IF 6.1) Pub Date : 2024-02-23 Katharina Schlünder, Madalena Cipriano, Aline Zbinden, Stefanie Fuchs, Torsten Mayr, Katja Schenke-Layland, Peter Loskill
-
Multifunctional cardiac microphysiological system based on transparent ITO electrodes for simultaneous optical measurement and electrical signal monitoring Lab Chip (IF 6.1) Pub Date : 2024-02-19 Zhangjie Li, Kai Niu, Chenyang Zhou, Feifan Wang, Kangyi Lu, Yijun Liu, Lian Xuan, Xiaolin Wang
-
Lab on skin: real-time metabolite monitoring with polyphenol film based subdermal wearable patches Lab Chip (IF 6.1) Pub Date : 2024-02-22 Georgeta Vulpe, Guoyi Liu, Sam Oakley, Guanghao Yang, Arjun Ajith Mohan, Mark Waldron, Sanjiv Sharma
-
Thermal segment microwell plate control for automated liquid handling setups Lab Chip (IF 6.1) Pub Date : 2024-02-21 Simon Seidael, Katja F. Winkler, Anke Kurreck, Mariano Nicolas Cruz-Bournazou, Katharina Paulick, Sebastian Groß, Peter Neubauer
-
From animal testing to in vitro systems: advancing standardization in microphysiological systems Lab Chip (IF 6.1) Pub Date : 2024-02-15 Darwin R. Reyes, Mandy B. Esch, Lorna Ewart, Rohollah Nasiri, Anna Herland, Kyung Sung, Monica Piergiovanni, Carolina Lucchesi, James T. Shoemaker, Jelena Vukasinovic, Hiroki Nakae, James Hickman, Kapil Pant, Anne Taylor, Niki Heinz, Nureddin Ashammakhi
-
SeParate: multiway fluorescence-activated droplet sorting based on integration of serial and parallel triaging concepts Lab Chip (IF 6.1) Pub Date : 2024-02-20 Wannes Verbist, Jolien Breukers, Sapna Sharma, Iene Rutten, Hans Gerstmans, Lotte Coelmont, Francesco Dal Dosso, Kai Dallmeier, Jeroen Lammertyn
-
A system for fluid pumping by liquid metal multi-droplets Lab Chip (IF 6.1) Pub Date : 2024-02-19 Liyu Dai, Xiaomin Wu, Huimin Hou, Zhifeng Hu, Yukai Lin, Zhiping Yuan
-
Microfluidic systems for infectious disease diagnostics Lab Chip (IF 6.1) Pub Date : 2024-02-19 Thomas Lehnert, Martin A. M. Gijs
-
A microfluidic chip for sustained oxygen gradient formation in the intestine ex vivo Lab Chip (IF 6.1) Pub Date : 2024-02-15 Lauren M. Delong, Colby E. Witt, Madison Pennell, Ashley E. Ross
-
Multifunctional flexible magnetic drive gripper for target manipulation in complex constrained environments Lab Chip (IF 6.1) Pub Date : 2024-02-19 Meiying Zhao, Ye Tao, Wenshang Guo, Zhenyou Ge, Hanqing Hu, Ying Yan, Chaoxia Zou, Guiyu Wang, Yukun Ren
-
Microfluidic impedance cytometry with flat-end cylindrical electrodes for accurate and fast analysis of marine microalgae Lab Chip (IF 6.1) Pub Date : 2024-02-19 Xiaoming Chen, Mo Shen, Shun Liu, Chungang Wu, Liangliang Sun, Zhipeng Song, Jishun Shi, Yulong Yuan, Yong Zhao
-
Comparison between dynamic versus static models and real-time monitoring of neuronal dysfunction in an amyloid-β induced neuronal toxic model on a chip platform Lab Chip (IF 6.1) Pub Date : 2024-02-19 Chu-Chun Liang, Po-Yen Chen, Nien-Che Liu, I-Chi Lee
-
Immune cells and inflammatory mediators cause endothelial dysfunction in a vascular microphysiological system Lab Chip (IF 6.1) Pub Date : 2024-02-16 Aishwarya Rengarajan, Hannah E. Goldblatt, David J. Beebe, María Virumbrales-Muñoz, Derek S. Boeldt
-
AMF-SporeChip provides new insights into arbuscular mycorrhizal fungal asymbiotic hyphal growth dynamics at the cellular level Lab Chip (IF 6.1) Pub Date : 2024-02-16 Felix Richter, Maryline Calonne-Salmon, Marcel G. A. van der Heijden, Stéphane Declerck, Claire E. Stanley