样式: 排序: IF: - GO 导出 标记为已读
-
A convenient method for the relative and absolute quantification of lipid components in liposomes by 1H- and 31P NMR-spectroscopy Chem. Phys. Lipids (IF 3.4) Pub Date : 2024-04-12 Andreas H. Franz, Nataliya M. Samoshina, Vyacheslav V. Samoshin
-
-
Comparison of structural effects of cholesterol, lanosterol, and oxysterol on phospholipid (POPC) bilayers Chem. Phys. Lipids (IF 3.4) Pub Date : 2024-02-06 Ayumi Okayama, Tatsuya Hoshino, Kohei Wada, Hiroshi Takahashi
-
Micelle formation of sodium taurolithocholate Chem. Phys. Lipids (IF 3.4) Pub Date : 2024-02-05 Keisuke Matsuoka, Rina Sekiguchi, Tomokazu Yoshimura
-
Non-lamellar lyotropic liquid crystalline nanoparticles as nanocarriers for enhanced drug encapsulation of atorvastatin calcium and proanthocyanidins Chem. Phys. Lipids (IF 3.4) Pub Date : 2024-02-05 Mardhiah Maslizan, Muhammad Salahuddin Haris, Mokrish Ajat, Siti Nurul Ain Md Jamil, Shah Christirani Azhar, N. Idayu Zahid, Intan Diana Mat Azmi
-
Bottom-up approach to explore alpha-amylase assisted membrane remodelling Chem. Phys. Lipids (IF 3.4) Pub Date : 2024-01-02 Harshit Kumar, Sayar Mandal, Reena Yadav, Suhasi Gupta, Hemraj Meena, Mayur Kadu, Rajni Kudawla, Pratibha Sharma, Indu Pal Kaur, Subhabrata Maiti, John H. Ipsen, Tripta Bhatia
Soluble alpha-amylases play an important role in the catabolism of polysaccharides. In this work, we show that the malt α -amylase can interact with the lipid membrane and further alter its mechanical properties. Vesicle fluctuation spectroscopy is used for quantitative measurement of the membrane bending rigidity of phosphatidylcholines lipid vesicles from the shape fluctuation based on the whole
-
The role of glucose and fructose on lipid droplet metabolism in human normal bronchial and cancer lung cells by Raman spectroscopy Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-12-29 Monika Kopec, Karolina Beton-Mysur
-
Novel bioactive lipids enhanced HDL-mediated cholesterol efflux from macrophages through the ABCA1 receptor pathway Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-12-15 Ali Khattib, Manar Shmet, Rasha Ashkar, Tony Hayek, Soliman Khatib
High-density lipoprotein (HDL) has traditionally been acknowledged as "good cholesterol" owing to its significant association with a decreased risk of atherosclerosis. This association is primarily attributed to HDL's direct involvement in cholesterol efflux capacity, which plays a pivotal role in reverse cholesterol transport. A novel active compound from Nannochloropsis microalgae termed lyso-DGTS
-
Structural changes in layers of lipid mixtures at low surface tensions Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-12-12 A.G. Bykov, M.A. Panaeva, O.Y. Milyaeva, A.V. Michailov, A.R. Rafikova, E. Guzman, R. Rubio, R. Miller, B.A. Noskov
-
Closer look at the calorimetric lower transition in lipid bilayers Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-12-09 Sophia A. Korono, John F. Nagle
The thermal behavior of unilamellar vesicles has been revisited with differential scanning calorimetry to address the issue of whether it is essential to include interactions between neighboring bilayers in theories and simulations of the ripple phase. The issue focuses on the lower, aka pretransition, and the ripple phase that clearly exists between the lower and main transitions in multilamellar
-
Effect of cationic dendrimer on membrane mimetic systems in the form of monolayer and bilayer Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-11-30 Biplab Roy, Pritam Guha, Chien-Hsiang Chang, Prasant Nahak, Gourab Karmakar, Alexey G. Bykov, Alexander V. Akentiev, Boris A. Noskov, Anuttam Patra, Kunal Dutta, Chandradipa Ghosh, Amiya Kumar Panda
-
Unsaturation of serine lipids modulating the interaction of a cytosporone with models of the external leaflet of tumorigenic cell membranes Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-11-30 Guilherme Nuñez Jaroque, Augusto Leonardo dos Santos, Patrícia Sartorelli, Luciano Caseli
-
Monitoring galactolipid digestion and simultaneous changes in lipid-bile salt micellar organization by real-time NMR spectroscopy Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-11-21 Moulay Sahaka, Olivier Bornet, Achille Marchand, Dominique Lafont, Brigitte Gontero, Frédéric Carrière, Hélène Launay
-
Interactions between macrophage membrane and lipid mediators during cardiovascular diseases with the implications of scavenger receptors Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-11-23 Sangeetha Ravi, Livya Catherene Martin, Mahalakshmi Krishnan, Manikandan Kumaresan, Beulaja Manikandan, Manikandan Ramar
-
Elucidating the functional role of human ABHD16B lipase in regulating triacylglycerol mobilization and membrane lipid synthesis in Saccharomyces cerevisiae Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-11-07 Raja Narayanasamy, Dandamudi Usharani, Ram Rajasekharan
-
A tribute to our friend and colleague Professor Richard M. Epand Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-10-28 Jose C. Bozelli, Raquel F. Epand, John Katsaras, Jesús Pérez-Gil
Abstract not available
-
Saturation of fatty acids in phosphatidic acid uniquely alters transthyretin stability changing morphology and toxicity of amyloid fibrils Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-10-17 Abid Ali, Kiryl Zhaliazka, Tianyi Dou, Aidan P. Holman, Dmitry Kurouski
-
The small-molecule kinase inhibitor ceritinib, unlike imatinib, causes a significant disturbance of lipid membrane integrity: A combined experimental and MD study Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-10-18 Markus Fischer, Meike Luck, Max Werle, Alexander Vogel, Mohammad Bashawat, Kai Ludwig, Holger A. Scheidt, Peter Müller
Ceritinib and imatinib are small-molecule protein kinase inhibitors which are applied as therapeutic agents against various diseases. The fundamentals of their clinical use, i.e. their pharmacokinetics as well as the mechanisms of the inhibition of the respective kinases, are relatively well studied. However, the interaction of the drugs with membranes, which can be a possible cause of side effects
-
Organic synthesis of 1,2-dipalmitoyl-rac-glycero-3-phosphatidylethanolamine and its effect on the induction of apoptosis in normal human lung fibroblasts Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-10-13 Beatriz Tlatelpa-Romero, David Atahualpa Contreras-Cruz, Gabriel Guerrero-Luna, María Guadalupe Hernández-Linares, Sinuhé Ruiz-Salgado, Criselda Mendoza-Milla, Yair Romero, René de-la-Rosa Paredes, Luis F. Oyarzábal, Diego Alejandro Mendoza-Sámano, Jiovani Alfredo Galván-León, Luis G. Vázquez-de-Lara
Background /objective The phospholipid 1,2-dipalmitoyl-rac-glycero-3-phosphatidylethanolamine (PE) comprises two fatty acid chains: glycerol, phosphate, and ethanolamine. PE participates in critical cellular processes such as apoptosis and autophagy, which places it as a target for designing new therapeutic alternatives in diseases such as pulmonary fibrosis. Therefore, this study aimed obtain PE through
-
Lipidomic analysis identified potential predictive biomarkers of statin response in subjects with Familial hypercholesterolemia Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-10-11 Alvaro Cerda, Raul Hernandes Bortolin, Marcos Yukio Yoshinaga, Renata Caroline Costa de Freitas, Carolina Dagli-Hernandez, Jessica Bassani Borges, Victor Fernandes de Oliveira, Rodrigo Marques Gonçalves, Andre Arpad Faludi, Gisele Medeiros Bastos, Rosario Dominguez Crespo Hirata, Mario Hiroyuki Hirata
-
Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-09-23 Monika Kopec, Karolina Beton-Mysur, Halina Abramczyk
-
The influence of Leucidal – eco-preservative from radish – on model lipid membranes and selected pathogenic bacteria Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-09-14 Beata Wyżga, Magdalena Skóra, Katarzyna Hąc-Wydro
-
Characterization of conformational states of POPC and DPPCd62 in POPC/DPPCd62/cholesterol mixtures using Raman spectroscopy Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-08-12 Yu.V. Zaytseva, I.V. Zaytseva, N.V. Surovtsev
-
Effects of ionic liquids on biomembranes: A review on recent biophysical studies Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-08-15 Saheli Mitra, Veerendra K. Sharma, Sajal K. Ghosh
-
-
In-plane and out-of-plane gigahertz sound velocities of saturated and unsaturated phospholipid bilayers from cryogenic to room temperatures Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-08-12 E.A. Dobrynina, V.A. Zykova, N.V. Surovtsev
Here, we examined the gigahertz sound velocities of hydrated multibilayers of saturated (1,2-dimyristoyl-sn-glycero-3-phosphocholine, DMPC) and unsaturated (1,2-dioleoyl-sn-glycero-3-phosphocholine, DOPC) phospholipids by Brillouin spectroscopy. Out-of-plane and in-plane (lateral) phonons were studied independently of each other. Similar strong temperature dependences of the sound velocities were found
-
Solubilization of biomimetic lipid mixtures by some commonly used non-ionic detergents Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-07-11 Amanda C. Caritá, Rafaela R.M. Cavalcanti, Mariana S.S. Oliveira, Karin A. Riske
-
Recent advances in regulating lipid metabolism to prevent coronary heart disease Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-07-04 Jingchun Du, Wei Wu, Boran Zhu, Weiwei Tao, Lina Liu, Xiaolan Cheng, Min Zhao, Jibiao Wu, Yunlun Li, Ke Pei
The pathogenesis of coronary heart disease is a highly complex process, with lipid metabolism disorders being closely linked to its development. Therefore, this paper analyzes the various factors that influence lipid metabolism, including obesity, genes, intestinal microflora, and ferroptosis, through a comprehensive review of basic and clinical studies. Additionally, this paper delves deeply into
-
Membrane lipid composition of Carnobacterium maltaromaticum CNCM I-3298, a highly cryoresistant lactic bacterium Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-07-05 HP. Ta, C. Clarisse, E. Maes, N. Yamakawa, Y. Guérardel, F. Krzewinski, W. Zarzycka, D. Touboul, A. Girardeau, F. Fonseca, A. Kermarrec, M. Viau, A. Riaublanc, MH. Ropers
The growing consumption of fermented products has led to an increasing demand for lactic acid bacteria (LAB), especially for LAB tolerant to freezing/thawing conditions. Carnobacterium maltaromaticum is a psychrotrophic and freeze-thawing resistant lactic acid bacterium. The membrane is the primary site of damage during the cryo-preservation process and requires modulation to improve cryoresistance
-
Transethosome: An ultra-deformable ethanolic vesicle for enhanced transdermal drug delivery Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-06-24 Alan Raj, Kamal Dua, Rajesh Sreedharan Nair, C. Sarath Chandran, Angel Treasa Alex
Drug delivery through the skin improves solubility, bioavailability, and unwanted systemic side effects of the drug. The selection of a suitable carrier is a challenging process. The conventional lipid vesicles have some limitations. They deliver the drug in the stratum corneum and have poor colloidal stability. Here comes the need for ultra-deformable lipid vesicles to provide the drug beyond the
-
The influence of amphiphilic carbosilane dendrons on lipid model membranes Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-06-23 Dominika Wrobel, Antonin Edr, Eliska Zemanova, Tomáš Strašák, Alena Semeradtova, Jan Maly
-
Effect of cholesterol on the ion-membrane interaction: Zeta potential and dynamic light scattering study Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-05-13 Kalyan Kumar Banerjee, Pabitra Maity, Surajit Das, Sanat Karmakar
Cholesterol in a bio-membrane plays a significant role in many cellular event and is known to regulate the functional activity of protein and ion channel. In this study we report a significant effect of cholesterol on the ion-membrane interaction. We prepare large unilamellar vesicles, composed of zwitterionic lipid DOPC and anionic lipid DOPG with different cholesterol concentration. Electrostatics
-
Comparative analysis of intercellular lipid organization and composition between psoriatic and healthy stratum corneum Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-05-06 Tomonobu Uchino, Daichi Kamiya, Hiroaki Yagi, Hiyori Fujino-Shimaya, Ichiro Hatta, Shun Fujimori, Yasunori Miyazaki, Yukako Kirishita, Yuko Sano, Hajime Mizuno, Kenichiro Todoroki, Yoshiyuki Kagawa
-
Porcine spermadhesin AQN-3 binds to negatively charged phospholipids Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-05-06 Karin Müller, Peter Müller, Fan Lui, Pascal D. Kroh, Beate C. Braun
-
Polymeric nanoparticles containing babassu oil: A proposed drug delivery system for controlled release of hydrophilic compounds Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-04-18 João Vitor Raupp de Oliveira, Pedro Leardin Silveira, Gabriela Spingolon, Gabriel Antonio Lopes Alves, Flávia Pires Peña, Tanira Alessandra Silveira Aguirre
-
Labyrinthopeptin A2 disrupts raft domains Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-04-14 José Villalaín
-
In silico and in vitro investigation of bile salts as coformers for edaravone coamorphous dispersion- Part I Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-04-07 Dhrumi Patel, Sarika Wairkar
-
Ionizable lipids penetrate phospholipid bilayers with high phase transition temperatures: perspectives from free energy calculations Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-03-31 Inna Ermilova, Jan Swenson
-
-
Atomic force microscopy study of the complexation of sterols and the glycoalkaloid α-tomatine in Langmuir-Blodgett monolayers Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-03-15 Bishal Nepal, Keith J. Stine
Glycoalkaloids are secondary metabolites produced by plants that aid in their protection from pathogens and pests. They are known to form 1:1 complexes with 3β-hydroxysterols such as cholesterol causing membrane disruption. So far, the visual evidence showcasing the complexes formed between glycoalkaloids and sterols in monolayers has been mainly restricted to some earlier studies using Brewster angle
-
Construction of redox-sensitive liposomes modified by glycyrrhetinic acid and evaluation of anti-hepatocellular carcinoma activity Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-03-15 Jie Hu, Yongsheng Zheng, Zhijie Wen, Hudie Fu, Xuedan Yang, Xuexin Ye, Shengpeng Zhu, Li Kang, Xiaojun Li, Xinzhou Yang, Yan Hu
-
In situ monitoring of galactolipid digestion by infrared spectroscopy in both model micelles and spinach chloroplasts Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-03-12 Moulay Sahaka, Eduardo Mateos-Diaz, Sawsan Amara, Jutarat Wattanakul, David Gray, Dominique Lafont, Brigitte Gontero, Hélène Launay, Frédéric Carrière
-
On the deformability of additivated phosphatidylcholine liposomes: Molecular dynamic regimes and membrane elasticity Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-02-24 M.B. Marzola Coronel, C.C. Fraenza, E. Anoardo
-
Cholesterol stabilization of phospholipid vesicles against bile-induced solubilization Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-02-20 Patrick Tai, Andrew J. Clulow, Ben J. Boyd, Matt Golding, Harjinder Singh, David W. Everett
Sphingomyelin (SM) and cholesterol complex to form functional liquid-ordered (Lo) domains. It has been suggested that the detergent resistance of these domains plays a key role during gastrointestinal digestion of the milk fat globule membrane (MFGM), which is rich in both SM and cholesterol. Small-angle X-ray scattering was employed to determine the structural alterations that occur when milk sphingomyelin
-
-
EGFR-targeted hybrid lipid nanoparticles for chemo-photothermal therapy against colorectal cancer cells Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-01-10 Fang Fang, Xinming Zhang, Jin Tang, Yu Wang, Jinchen Xu, Yu Sun
-
Interaction of psychedelic tryptamine derivatives with a lipid bilayer Chem. Phys. Lipids (IF 3.4) Pub Date : 2023-01-07 Fateme Zohairi, Himanshu Khandelia, Ali Asghar Hakami Zanjani
-
-
A Lipid Activatable Fluorescence Probe for Atherosclerosis Imaging Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-12-26 Bing Han, Ming Bai, Jin Zhang, Xiaoxue Meng, Zheng Zhang
Lipid has been considered as a promising target for atherosclerosis diagnosis. However, there is still no available lipid imaging technology in clinic. Herein, we have prepared a fluorescence probe TPN for lipid-specific imaging in atherosclerosis. TPN exhibited extremely weak emission in water, while its emission was significantly enhanced in lipid environment at 666 nm. Meanwhile, TPN has showed
-
Towards understanding the binding affinity of lipid drug carriers to serum albumin Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-12-09 Katarzyna Dopierała, Marek Weiss, Martyna Krajewska, Justyna Błońska
-
Development of skin-permeable flexible liposome using ergosterol esters containing unsaturated fatty acids Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-12-07 Sehyeon Park, Hyung Kwoun Kim
-
Fatty acid transport proteins (FATPs) in cancer Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-11-30 Ranjitha Acharya, Shilpa S. Shetty, Suchetha Kumari N
Lipids play pivotal roles in cancer biology. Lipids have a wide range of biological roles, especially in cell membrane synthesis, serve as energetic molecules in regulating energy-demanding processes; and they play a significant role as signalling molecules and modulators of numerous cellular functions. Lipids may participate in the development of cancer through the fatty acid signalling pathway. Lipids
-
Effect of the CER[NP]:CER[AP] a ratio on the structure of a stratum corneum model lipid matrix - a molecular dynamics study Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-11-15 Natalia Rivero, Martha C. Daza, Markus Doerr
In some dermal diseases with evident skin dehydration and desquamation, the natural ratio of CER[NP]:CER[AP] is altered in the extracellular matrix of the stratum corneum by increasing the concentration of CER[AP]. The extracellular matrix of the stratum corneum is composed of several stacked lipid bilayers. Molecular dynamics simulations were used to investigate the molecular nanostructure of CER[NP]
-
Challenges and emerging strategies for next generation liposomal based drug delivery: An account of the breast cancer conundrum Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-11-12 Aliesha Moudgil, Rajesh Salve, Virendra Gajbhiye, Bhushan P. Chaudhari
-
Nanostructured lipid carrier-loaded metformin hydrochloride: Design, optimization, characterization, assessment of cytotoxicity and ROS evaluation Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-11-11 Meghanath B. Shete, Ashwini S. Deshpande, Pravin K. Shende
-
Synthetic star shaped tetra-tailed biocompatible supramolecular amphiphile as an efficient nanocarrier for Amphotericin B Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-11-10 Imdad Ali, Samiullah Burki, Jawad ur Rehman, Shafi Ullah, Ibrahim Javid, Magda H. Abdellattif, Muhammad Raza Shah
-
Synchrotron-based infrared microspectroscopy of polymeric nanoparticles and skin: Unveiling molecular interactions to enhance permeation Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-10-21 Sofia A. Costa Lima, Ana Isabel Barbosa, Cláudia Nunes, Ibraheem Yousef, Salette Reis
-
Modulation of function and structure of stratum corneum in sphingomyelin synthase 2-deficient mice Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-10-21 Nozomi Honma, Ichiro Hatta, Toshiro Okazaki, Yoshihiro Tokudome
Sphingomyelin synthase (SMS) synthesizes sphingomyelin (SM) from ceramide (Cer), a precursor of Cer. The effects of SMS deficiency on stratum corneum (SC) barrier function and SC lamellar structure are unknown. In this report, permeation of hydrophilic and lipophilic compounds through full-thickness skin or stripped skin of SMS2-knockout (KO) and wild-type (WT) mice was examined. Furthermore, small-angle
-
Colloidal delivery of vitamin E into solid lipid nanoparticles as a potential complement for the adverse effects of anemia treatment Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-10-20 Rocío C. Gambaro, Ignacio Rivero Berti, Maximiliano L. Cacicedo, Stephan Gehring, Vera A. Alvarez, Guillermo R. Castro, Analía Seoane, Gisel Padula, German A. Islan
-
Effect of polyols on membrane structures of liposomes: A study using small-angle X-ray scattering data and generalized indirect Fourier transformation Chem. Phys. Lipids (IF 3.4) Pub Date : 2022-10-20 Aika Sekine, Taku Ogura, Koji Tsuchiya, Kaoru Ohishi, Yuji Masubuchi, Masaaki Akamatsu, Kenichi Sakai, Masahiko Abe, Hideki Sakai