-
mTOR and neuroinflammation in epilepsy: implications for disease progression and treatment Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-03-26 Teresa Ravizza, Mirte Scheper, Rossella Di Sapia, Jan Gorter, Eleonora Aronica, Annamaria Vezzani
-
Coding corners Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-03-14 Katherine Whalley
Neurons in the mouse subiculum encode concave and convex geometrical environmental features.
-
Barriers and brain fog Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-03-14 Sian Lewis
One of the long-term sequelae associated with SARS-CoV-2 infection is ‘brain fog’, which is shown in this study to be linked to systemic inflammation and leakiness of the blood–brain barrier.
-
How the brain’s primary processing units compute to give rise to intelligence Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-03-13 Ning-long Xu
Ning-long Xu discusses a 1999 paper that outlined a mechanism by which cortical pyramidal neurons integrate layer-specific inputs.
-
Fear bypasses the amygdala Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-03-08 Sian Lewis
Innate fear-like responses are thought to involve the amygdala, but here a tetra-synaptic pathway is identified that mediates odour-evoked innate fear in mice.
-
Preparatory activity and the expansive null-space Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-03-05 Mark M. Churchland, Krishna V. Shenoy
-
Overnight neuronal plasticity and adaptation to emotional distress Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-03-05 Yesenia Cabrera, Karin J. Koymans, Gina R. Poe, Helmut W. Kessels, Eus J. W. Van Someren, Rick Wassing
-
MMP8 and stress susceptibility Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-03-04 Darran Yates
Increased levels of matrix metalloproteinase 8, expressed by circulating myeloid cells, may have a role in stress-induced changes in social behaviour in mice.
-
Social representation Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-03-04 Katherine Whalley
Populations of neurons in the mouse hippocampus use distinct representational strategies to encode familiarity and episodic social memory.
-
Olfactory neurons can feel the (heart) beat Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-02-26 Katherine Whalley
Blood pressure pulsations modulate the activity of neurons in the rodent olfactory bulb via the mechanosensitive ion channel PIEZO2
-
Response sub-additivity and variability quenching in visual cortex Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-02-19 Robbe L. T. Goris, Ruben Coen-Cagli, Kenneth D. Miller, Nicholas J. Priebe, Máté Lengyel
-
Linking activity dyshomeostasis and sleep disturbances in Alzheimer disease Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-02-19 Inna Slutsky
-
The human hippocampus beyond episodic memory Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-02-08 Valeria Della-Maggiore
In this Journal Club, Valeria Della-Maggiore highlights a 2017 paper that provided key evidence for a role for the hippocampus in motor skill learning
-
Neural circuits of long-term thermoregulatory adaptations to cold temperatures and metabolic demands Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-02-05 Clarissa M. D. Mota, Christopher J. Madden
-
The cognitive impact of light: illuminating ipRGC circuit mechanisms Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-26 Heather L. Mahoney, Tiffany M. Schmidt
-
Neurons in the hypothalamus counteract ageing in mice Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-25 Joseph Willson
In mice, a subset of neurons in the dorsomedial hypothalamus control sympathetic nervous system signalling to adipose tissue and are dysregulated with age; activating these neurons prolongs lifespan and slows the decline in physical activity associated with ageing.
-
Curiosity: primate neural circuits for novelty and information seeking Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-23 Ilya E. Monosov
-
Goal-directed learning in adolescence: neurocognitive development and contextual influences Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-23 Linda Wilbrecht, Juliet Y. Davidow
-
Tightening synaptic relations Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-19 Lisa Heinke
A study analyses the nanotopography of presynaptic calcium channels and release sensors and the degree of their coupling during maturation of an inhibitory synapse.
-
Causation in neuroscience: keeping mechanism meaningful Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-11 Lauren N. Ross, Dani S. Bassett
-
Cell type-specific roles of APOE4 in Alzheimer disease Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-08 Jessica Blumenfeld, Oscar Yip, Min Joo Kim, Yadong Huang
-
Data-driven modelling of neurodegenerative disease progression: thinking outside the black box Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-08 Alexandra L. Young, Neil P. Oxtoby, Sara Garbarino, Nick C. Fox, Frederik Barkhof, Jonathan M. Schott, Daniel C. Alexander
-
A neuronal cluster involved in arousal and breathing Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-04 Darran Yates
A study reveals a subpopulation of neuropeptide S-expressing neurons that regulates arousal and breathing.
-
Mistaken identity Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-05 Sian Lewis
Around 10% of individuals with frontotemporal lobar dementia have amyloid filament inclusions that lack tau and TDP-43 and were thought to contain the protein FUS, but are found instead to contain the FUS homologue TAF15.
-
A neuronal subcompartment view of ATP production Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-05 Darran Yates
A study indicates that different mechanisms of ATP production predominate in different cellular subcompartments in neurons.
-
Orchestrating axonal organization Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-05 Lisa Heinke
Cytoplasmic mislocalization of TDP-43 in neurodegenerative disease affects mRNA maturation and protein levels of stathmin-2, leading to a reduction in axon diameter and tearing of outer myelin layers and thereby disrupting neuronal function.
-
Promoting axon regeneration after injury Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-04 Darran Yates
A study in mice identifies formin 2 as a regulator of axon regeneration and a potential target for promoting nerve repair after peripheral nerve injury.
-
Understanding neural circuit function through synaptic engineering Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2024-01-03 Ithai Rabinowitch, Daniel A. Colón-Ramos, Michael Krieg
-
Self-recognition mirrored from others Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-22 Jake Rogers
A mark test of self-recognition in mice reveals that self-responding ventral CA1 neurons underlie mirror-induced self-directed behaviour and are shaped by social experience with conspecifics.
-
Controlling communication Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-19 Katherine Whalley
A small population of neurons in the mouse brainstem coordinate sound production and volume control during vocalizations.
-
Benefit worth the cost Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-15 Jake Rogers
A study in mice helps to resolve a debate surrounding striatal DA dynamics and reward benefit or cost and also reveals motivation and transient striatal DA release have a bidirectional causal relationship.
-
Preparing for motherhood Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-08 Katherine Whalley
In mice, specific pools of adult neural stem cells are recruited during pregnancy to support postpartum maternal behaviour.
-
The neurobiology of SARS-CoV-2 infection Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-04 Jenny Meinhardt, Simon Streit, Carsten Dittmayer, Regina v. Manitius, Helena Radbruch, Frank L. Heppner
-
The long COVID haul Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-30 Sian Lewis
Ongoing systemic and neurocognitive impairments that continue in a subset of individuals after infection with SARS-CoV-2 infection are found to be associated with reduced serotonin levels.
-
Sleep and circadian rhythmicity as entangled processes serving homeostasis Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-01 Paul Franken, Derk-Jan Dijk
-
The generative grammar of the brain: a critique of internally generated representations Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-30 George Dragoi
-
From local APP expression to network dysfunction Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-29 Darran Yates
In mice, localized mutant APP expression in the CA3 hippocampal region leads to progressive network dysfunction and hippocampus-dependent memory deficits.
-
Publisher Correction: The transition to motherhood: linking hormones, brain and behaviour. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-01 Camila Servin-Barthet,Magdalena Martínez-García,Clara Pretus,Maria Paternina-Die,Anna Soler,Olha Khymenets,Óscar J Pozo,Benedetta Leuner,Oscar Vilarroya,Susana Carmona
-
Human neuronal maturation comes of age: cellular mechanisms and species differences Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-23 Jenelle L. Wallace, Alex A. Pollen
-
Low-frequency neural parsing of hierarchical linguistic structures. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-01 Nai Ding
-
Reply to 'Low-frequency neural parsing of hierarchical linguistic structures'. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-01 Nina Kazanina,Alessandro Tavano
-
Playing tag at the axon Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-15 Lisa Heinke
A new biotinylation-based approach identifies previously unknown cell surface proteins of the axonal initial segment (AIS) and shows a role for contactin-1 in assembly of the AIS extracellular matrix.
-
Sometimes science needs a stubborn mind: the discovery of dopamine Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-14 Federica De Lazzari
Federica De Lazzari describes Arvid Carlsson’s 1957 paper, which provided evidence for the importance of dopamine in brain function.
-
Mapping cilia connections in the human brain Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-13 Katherine Whalley
The organization and diversity of neuronal and glial primary cilia and their connectivity in the human cortex is characterized in detail.
-
Avoiding bias in fluorescence sensor readout Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-10 Dmitri A. Rusakov
-
Reliable social switch Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-08 Jake Rogers
The macaque homologue of the dorsal medial prefrontal cortex tracks the reliability of social information and determines whether this information is used to guide choices during decision making.
-
Caught in a trap Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-02 Katherine Whalley
Ketamine is ‘trapped’ in the pores of NMDA receptors in the lateral habenula, mediating sustained antidepressant effects in mice.
-
Boundary deprivation does not prevent grid cell maturation Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-01 Caroline Barranco
Grid cells develop in rats soon after they leave the nest. Here, Ulsaker-Janke et al. show that preventing exposure to straight boundaries from birth delays, but does not prevent, grid cell maturation in adult rats.
-
Coding number estimates Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-31 Darran Yates
A new study shows that, in a numerical judgement task, individuals show differences in neuronal coding of numbers below and above approximately four in the medial temporal lobe.
-
Reply to 'What oscillations can do for syntax depends on your theory of structure building'. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-01 Nina Kazanina,Alessandro Tavano
-
What oscillations can do for syntax depends on your theory of structure building. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-01 Cas W Coopmans,Anna Mai,Sophie Slaats,Hugo Weissbart,Andrea E Martin
-
When linguistic dogma rejects a neuroscientific hypothesis. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-01 Chia-Wen Lo,Lena Henke,Jordi Martorell,Lars Meyer
-
How deep is the brain? The shallow brain hypothesis Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-27 Mototaka Suzuki, Cyriel M. A. Pennartz, Jaan Aru
-
Detection, processing and reinforcement of social cues: regulation by the oxytocin system Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-27 Rohit Menon, Inga D. Neumann
-
Data sharing in neuroimaging: experiences from the BIDS project Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-24 Melanie Ganz, Russell A. Poldrack
Data sharing is an essential component of open science practice. The Brain Imaging Data Structure project has pioneered a way to organize neuroimaging and behavioural data that enables easy sharing and reuse. We present experiences from the BIDS project and highlight how standards can promote open science.
-
Neuron–oligodendroglial interactions in health and malignant disease Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-19 Kathryn R. Taylor, Michelle Monje
-
Give and take Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-18 Sian Lewis
Following synaptic vesicle exocytosis, synaptotagmin 1 recruits a lipid signalling pathway within the presynaptic plasma membrane that drives local dynamin recruitment and membrane retrieval by endocytosis, thus maintaining membrane homeostasis.
-
Towards a biologically annotated brain connectome Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-17 Vincent Bazinet, Justine Y. Hansen, Bratislav Misic
-
Examining the role of the locus coeruleus in activating cortical astrocytes Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-06 Nathan Anthony Smith
In this Journal Club, Nathan Anthony Smith discusses a 2008 paper that documented a link between the noradrenergic modulatory network in the locus coeruleus and cortical astrocytes in vivo.
-
Reconstructing computational system dynamics from neural data with recurrent neural networks Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-04 Daniel Durstewitz, Georgia Koppe, Max Ingo Thurm