RSC主编推荐：有机领域精彩文章快览（免费阅读原文）

英国皇家化学会（RSC）是一个拥有超过175年历史的面向全球化学家的非营利会员制机构，旗下拥有43种期刊，其中很多在化学领域有很高影响力。为了进一步帮助广大读者追踪科技前沿热点，X-MOL团队与英国皇家化学会合作，推出英国皇家化学会期刊主编推荐的精彩文章快览，本期文章属“有机领域”，英文点评来自英国皇家化学会期刊的主编。如果大家对我们的解读有更多的补充和点评，欢迎在文末写评论发表您的高见！

Chemical Science (IF: 8.668)

1. Pd(II)-catalyzed synthesis of bifunctionalized carboranes via cage B–H activation of 1-CH₂NH₂-o-carboranes

Chem. Sci., 2018, Advance Article

DOI: 10.1039/C8SC01154K

Scientists in China report that the reversible conversion of o-carboranyl methylamines into bidentate imines initiates Pd-mediated cage B-H activation. The group isolated an amine coordinated Pd(II) complex that was shown to be the catalytically active intermediate for highly-selective B-H diarylation of o-carboranyl methylamines. Using glyoxylic acid as a directing agent, a series of B(4,5)-diarylated free primary o-carboranyl methylamines were obtained. These findings will be useful for the synthesis of bifunctionalized carboranes for pharmaceutical applications.

江南大学和南京大学的研究人员报道了o-碳硼烷基甲胺可逆转化为双齿鳌合的亚胺，从而引发钯（Pd）介导的笼状B-H键活化。他们还分离出一种胺配位的Pd(II)配合物，可用作o-碳硼烷基甲胺B-H键二芳基化反应的高选择性催化活性中间体。在使用乙醛酸作为导向剂时，他们得到一系列B(4,5)-二芳基化的游离一级o-碳硼烷基甲胺。这些发现将有助于药物研发中双功能碳硼烷的合成。

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2. Mechano-induced persistent room-temperature phosphorescence from purely organic molecules

Chem. Sci., 2018, Advance Article

DOI: 10.1039/C8SC00429C

Researchers in the UK and China report a persistent room temperature phosphorescence (RTP) from an organic material that can be induced by mechanical action. In its crystalline state, it has an emission lifetime of 0.15s at room temperature, which arises from the intermolecular electronic coupling of units with different excited state configurations. The group observed that two different crystals could be grown from this material, with and without mechano-induced persistent RTP. The mechano-luminescence depends upon the crystals' intermolecular interactions.

中山大学和英国达勒姆大学的研究人员合作报道了一种力学作用诱导产生持久室温磷光（RTP）的有机材料。在晶体状态下，基于不同激发态构型单元的分子间电子偶合作用，该材料在室温下的发射寿命为0.15秒。该课题组观察到，这种材料能够形成两种不同的晶体，仅其中一种具有力学作用诱导的持久RTP。这种力致发光取决于晶体的分子间相互作用。

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Organic Chemistry Frontiers (IF: 4.955)

1. Controllable synthetic ion channels

Org. Chem. Front., 2018, Advance Article

DOI: 10.1039/C8QO00287H

The author provided a comprehensive review on the development of synthetic ion channels with controllable transport behaviour over the past three decades. The most inspiring channels with voltage-, ligand-, light- and mechano-gating, as well as rectifying behaviours have been discussed in regard to their structures and functions in the hope of providing an easily accessible understanding of the field to the general reader. In addition, promising directions and major remaining challenges are also addressed.

该文章的作者全面综述了具有可控运输行为的合成离子通道在过去三十年的发展，并对极具启发意义的电压、配体、光和机械门控通道以及整流行为就其结构和功能进行了讨论，希望借此将该领域通俗易懂地普及给读者。另外，作者还对未来有研究前景的方向和存在的挑战进行了展望。

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2. Asymmetric total syntheses of callistrilones B, G and J

Org. Chem. Front., 2018, Advance Article

DOI: 10.1039/C8QO00130H

A very concise approach for the first asymmetric and scalable total syntheses of callistrilones B, G and J has been developed. These syntheses proceeded in only 3–4 steps from the commercially available (−)-α-phellandrene (8), without the need for protecting groups. The key feature of the syntheses was a biomimetic, diastereo- and regioselective oxidative [3 + 2] cycloaddition.

研究人员首次发展了一种不对称和可扩大规模的callistrilones B、G和J的全合成方法。合成中无需使用保护基团，从市售的(−)-α-水芹烯（8）出发只需要3到4步。合成的关键是仿生、非对映选择性和区域选择性的氧化[3 + 2]环加成过程。

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