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Evolution of flower color pattern through selection on regulatory small RNAs
Science ( IF 56.9 ) Pub Date : 2017-11-16 , DOI: 10.1126/science.aao3526
Desmond Bradley 1 , Ping Xu 2 , Irina-Ioana Mohorianu 2, 3 , Annabel Whibley 1 , David Field 4, 5 , Hugo Tavares 1 , Matthew Couchman 1 , Lucy Copsey 1 , Rosemary Carpenter 1 , Miaomiao Li 6, 7 , Qun Li 6 , Yongbiao Xue 6, 7, 8 , Tamas Dalmay 2 , Enrico Coen 1
Affiliation  

How the snapdragon chooses its color In some snapdragons, a yellow spot in a field of magenta shows the bee the best place to go. Flowers of a related subspecies are mainly yellow with magenta veins marking the target. Bradley et al. analyzed a locus that regulates the pattern of color. The locus contains an inverted gene duplication that encodes small RNAs that repress pigment biosynthesis. Analysis of flowers derived from a region of the Pyrenees where the subspecies coexist indicates that natural selection is operating upon the locus. Science, this issue p. 925 Population-wide differences in color patterns in snapdragon flowers are caused by an inverted gene duplication that generates small RNAs. Small RNAs (sRNAs) regulate genes in plants and animals. Here, we show that population-wide differences in color patterns in snapdragon flowers are caused by an inverted duplication that generates sRNAs. The complexity and size of the transcripts indicate that the duplication represents an intermediate on the pathway to microRNA evolution. The sRNAs repress a pigment biosynthesis gene, creating a yellow highlight at the site of pollinator entry. The inverted duplication exhibits steep clines in allele frequency in a natural hybrid zone, showing that the allele is under selection. Thus, regulatory interactions of evolutionarily recent sRNAs can be acted upon by selection and contribute to the evolution of phenotypic diversity.

中文翻译:

通过对调节性小 RNA 的选择来进化花色图案

金鱼草如何选择颜色 在一些金鱼草中,洋红色田野中的黄色斑点表明蜜蜂是最好的去处。相关亚种的花主要是黄色,带有标记目标的洋红色脉。布拉德利等人。分析了一个调节颜色模式的位点。该基因座包含一个反向基因重复,它编码抑制色素生物合成的小 RNA。对来自亚种共存的比利牛斯山脉地区的花朵的分析表明,自然选择正在该地区进行。科学,这个问题 p。925 金鱼草花颜色模式的全种群差异是由产生小 RNA 的反向基因复制引起的。小 RNA (sRNA) 调节植物和动物的基因。这里,我们表明,金鱼草花中颜色模式的人群差异是由产生 sRNA 的反向重复引起的。转录本的复杂性和大小表明重复代表了 microRNA 进化途径的中间体。sRNA 抑制色素生物合成基因,在传粉媒介进入的部位产生黄色高光。反向重复在自然杂交区的等位基因频率上表现出陡峭的克隆,表明等位基因处于选择状态。因此,进化上最近的 sRNA 的调节相互作用可以通过选择起作用,并有助于表型多样性的进化。转录本的复杂性和大小表明重复代表了 microRNA 进化途径的中间体。sRNA 抑制色素生物合成基因,在传粉媒介进入的部位产生黄色高光。反向重复在自然杂交区的等位基因频率上表现出陡峭的克隆,表明等位基因处于选择状态。因此,进化上最近的 sRNA 的调节相互作用可以通过选择起作用,并有助于表型多样性的进化。转录本的复杂性和大小表明重复代表了 microRNA 进化途径的中间体。sRNA 抑制色素生物合成基因,在传粉媒介进入的部位产生黄色高光。反向重复在自然杂交区的等位基因频率上表现出陡峭的克隆,表明等位基因处于选择状态。因此,进化上最近的 sRNA 的调节相互作用可以通过选择起作用,并有助于表型多样性的进化。
更新日期:2017-11-16
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