A copper-catalyzed intermolecular thioamination of maleimides with thiols and amines has been developed. A diverse range of 3-amino-4-thiomaleimides and 3,4-dihydropyrrolo[3,4-b][1,4]thiazine-5,7(2H,6H)-diones were obtained with good yields, involving C−N and C−S bond formations. This methodology is very practical and features high atom economy, excellent functional group tolerance.

中文翻译：

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马来酰亚胺，硫醇和胺的三组分偶联反应：铜催化的C（sp2）-H硫胺基化一步构建3,4-杂原子官能化的马来酰亚胺

已经开发了铜催化马来酰亚胺与硫醇和胺的分子间硫代胺化。获得了各种3-氨基-4-硫代马来酰亚胺和3,4-二氢吡咯并[3,4- b ] [1,4]噻嗪-5,7（2 H，6 H）-二酮，收率高，涉及CN和CS键的形成。该方法非常实用，具有高原子经济性，出色的官能团耐受性。