The diagnosis of Alzheimer's disease in research settings has evolved rapidly over the past decade, with both the International Working Group (IWG) and the US National Institute on Aging and Alzheimer's Association (NIA-AA) contributing to endeavours to integrate biomarkers into research diagnostic criteria. These efforts have been important to distinguish the range of disease stages, from asymptomatic to severe dementia. The NIA-AA work group is now proposing a draft research framework that builds upon the 2011 NIA-AA and 2014 IWG criteria to include biomarkers more comprehensively than previously.

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阿尔茨海默氏病：研究诊断标准的演变

在过去的十年中，研究环境中阿尔茨海默氏病的诊断发展迅速，国际工作组（IWG）和美国国家老龄研究所和阿尔茨海默氏症协会（NIA-AA）都为将生物标志物纳入研究诊断标准做出了贡献。这些努力对于区分从无症状到严重痴呆的疾病阶段范围非常重要。NIA-AA工作组现在正在提议一个研究框架草案，该框架以2011年NIA-AA和2014年IWG标准为基础，以比以前更全面地包括生物标志物。