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Systemic Delivery of Bc12-Targeting siRNA by DNA Nanoparticles Suppresses Cancer Cell Growth
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2017-11-15 05:26:05 , DOI: 10.1002/anie.201709485 Mohammad Aminur Rahman 1 , Pengfei Wang 2 , Zhixiang Zhao 1, 3 , Dongsheng Wang 1 , Sreenivas Nannapaneni 1 , Chao Zhang 4 , Zhengjia Chen 4 , Christopher C. Griffith 5 , Selwyn J. Hurwitz 6 , Zhuo G. Chen 1 , Yonggang Ke 2 , Dong M. Shin 1, 2
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2017-11-15 05:26:05 , DOI: 10.1002/anie.201709485 Mohammad Aminur Rahman 1 , Pengfei Wang 2 , Zhixiang Zhao 1, 3 , Dongsheng Wang 1 , Sreenivas Nannapaneni 1 , Chao Zhang 4 , Zhengjia Chen 4 , Christopher C. Griffith 5 , Selwyn J. Hurwitz 6 , Zhuo G. Chen 1 , Yonggang Ke 2 , Dong M. Shin 1, 2
Affiliation
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DNPs can deliver: DNA nanoparticles (DNPs) were utilized as vehicles for the systemic delivery of siRNA to suppress tumor growth by specifically knocking down an anti-apoptotic protein Bcl2.
中文翻译：
DNA纳米粒子的Bc12靶向siRNA的系统传递抑制癌细胞的生长。
DNP可以递送：DNA纳米颗粒（DNP）被用作siRNA全身性递送的载体，通过特异性敲低抗凋亡蛋白Bcl2来抑制肿瘤的生长。
更新日期：2017-11-15
中文翻译：
DNA纳米粒子的Bc12靶向siRNA的系统传递抑制癌细胞的生长。
DNP可以递送：DNA纳米颗粒（DNP）被用作siRNA全身性递送的载体，通过特异性敲低抗凋亡蛋白Bcl2来抑制肿瘤的生长。
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