The emerging pathogen Candida auris has been associated with nosocomial outbreaks on five continents. Genetic analysis indicates the simultaneous emergence of separate clades of this organism in different geographical locations. Invasive infection and colonization have been detected predominantly in patients in high-dependency settings and have garnered attention due to variable antifungal resistance profiles and transmission within units instituting a range of infection prevention and control measures. Issues with the identification of C. auris using both phenotypic and molecular techniques have raised concerns about detecting the true scale of the problem. This review considers the literature available on C. auris and highlights the key unknowns, which will provide direction for further work in this field.

中文翻译：

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耳念珠菌：文献综述 [评论]

新出现的病原体耳念珠菌与五大洲的医院内暴发有关。遗传分析表明该生物体的不同进化枝在不同地理位置同时出现。侵袭性感染和定植主要在高度依赖环境的患者中检测到，并且由于不同的抗真菌耐药性以及在采取一系列感染预防和控制措施的单位内传播而引起了人们的关注。使用表型和分子技术鉴定耳念珠菌的问题引起了人们对检测问题真实规模的担忧。本综述考虑了有关耳念珠菌的现有文献，并强调了关键的未知因素，这将为该领域的进一步工作提供方向。