A series of novel blue-light-emitting 2 H -imidazo[5,1- a ]isoquinolinium chloride derivatives were synthesized by the reaction of isoquinoline with trifluoroacetimidoyl chlorides and isocyanides in dry CH 2 Cl 2 in excellent yields. Fluorescence studies showed that the compounds absorb UV radiation and then emit blue light at about 481 nm with moderate to good fluorescence quantum yields. These compounds also showed high Stokes shifts, and can be used to develop ­ultrasensitive fluorescent molecular probes to study a variety of biological events and processes.

中文翻译：

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3-(三氟甲基)-2H-咪唑并[5,1-a]异喹啉氯化物衍生物的合成及光物理性质

通过异喹啉与三氟乙酰亚胺酰氯和异氰化物在干燥 CH 2 Cl 2 中的反应，以优异的产率合成了一系列新型的蓝色发光 2 H-咪唑并[5,1-a]异喹啉氯化物衍生物。荧光研究表明，这些化合物吸收紫外线辐射，然后以中等至良好的荧光量子产率发射约 481 nm 的蓝光。这些化合物还表现出高斯托克斯位移，可用于开发超灵敏荧光分子探针，以研究各种生物事件和过程。