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Recent advancements in the synthesis of pentafluorosulfanyl (SF5)-containing heteroaromatic compounds
Tetrahedron Letters ( IF 1.8 ) Pub Date : 2017-11-07 , DOI: 10.1016/j.tetlet.2017.11.015
Prajwalita Das , Etsuko Tokunaga , Norio Shibata

The unique features of the pentafluorosulfanyl (SF5) group have made it renowned as a “super trifluoromethyl (CF3)” group. Owing to the big success of CF3-containing heteroaromatic compounds in medicinal chemistry, agro-chemistry and material sciences, SF5-substituted heteroaromatic compounds have gained a lot of attention in very recent years as novel and potential candidates in these fields. However, the synthetic methodology for SF5-substituted heteroaromatic compounds is still highly limited. This digest highlights the recent, rapid, and significant advances made in the synthesis of SF5-heteroaromatics.



中文翻译:

含五氟硫烷基(SF 5)的杂芳族化合物的合成新进展

五氟硫基(SF 5)基团的独特功能使其成为“超级三氟甲基(CF 3)”基团。由于含CF 3的杂芳族化合物在药物化学,农业化学和材料科学领域取得了巨大的成功,因此,SF 5取代的杂芳族化合物作为这些领域中的新型和潜在候选物已在最近几年受到了广泛的关注。然而,用于SF 5取代的杂芳族化合物的合成方法仍然高度受限。此摘要突出显示了SF 5-杂芳族化合物的合成的最新,快速且重要的进展。

更新日期:2017-11-07
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