Furofurans are one of the largest sub-types of classical lignans which have been found to possess a broad range of important biological activities. Tremendous efforts have been directed to develop synthetic methodologies for the synthesis of furofurans, especially in a stereoselective manner, due to their interesting bioactivities associated with the structural and stereochemical complexity. This article summarizes the reports on asymmetric synthesis of furofurans disclosed during the period of 2004–2017.

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呋喃呋喃的不对称合成

呋喃呋喃是经典木脂素的最大亚型之一，已发现其具有广泛的重要生物活性。由于其与结构和立体化学复杂性相关的令人感兴趣的生物活性，已经进行了巨大的努力以开发用于合成呋喃呋喃的合成方法，特别是以立体选择性的方式。本文总结了2004-2017年间有关呋喃呋喃的不对称合成的报道。