Over two decades, there has been debate about whether there is a specific cardiovascular risk associated with high increments in postload glucose concentrations, over and above the risk conferred by dysglycaemia (slightly raised plasma glucose concentrations not necessarily diagnostic for diabetes) or hyperglycaemia (abnormally high plasma glucose concentrations compatible with a diagnosis of diabetes). Are the results of oral glucose tolerance testing or glycaemic excursions after mixed meals¹ more important than fasting glucose and HbA_1c concentrations? Epidemiological data suggest that postload glycaemic excursions are more closely linked to cardiovascular events,¹ but even slightly raised fasting plasma glucose concentrations are predictive of cardiovascular events as well.

中文翻译：

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代替ACE的断点：阿卡波糖，负荷后血糖漂移和心血管事件

在过去的二十多年中，关于是否存在与后负荷葡萄糖浓度高增加相关的特定心血管疾病风险，而不仅仅是由血糖异常（血浆葡萄糖浓度略微升高，不一定能诊断出糖尿病）或高血糖（异常高）所带来的风险。血浆葡萄糖浓度与糖尿病的诊断兼容）。混合餐后口服葡萄糖耐量测试或血糖波动¹的结果是否比空腹血糖和HbA _1c的浓度重要？流行病学数据表明，负荷后血糖波动与心血管事件更为紧密相关，[ ^1] 但即使空腹血糖浓度稍微升高，也可以预测心血管事件。