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Iodine supplementation in pregnancy in mildly deficient regions
The Lancet Diabetes & Endocrinology ( IF 44.5 ) Pub Date : 2017-10-10 , DOI: 10.1016/s2213-8587(17)30331-5
Sarah C Bath

It is well known that severe iodine deficiency during pregnancy affects fetal brain development and has implications for cognition in later life, including reduced intelligence quotient (IQ) scores.1 However, the effects of mild-to-moderate deficiency during pregnancy are less well known. Findings of observational studies in mildly-to-moderately iodine-deficient pregnant women have shown an association with lower IQ, reading ability,2 and spelling scores in offspring.3 Although several randomised controlled trials of iodine supplementation in pregnancy have been done in regions of mild-to-moderate iodine deficiency, they did not measure neurodevelopment in offspring.

中文翻译:

轻度贫血地区孕妇补充碘

众所周知,怀孕期间严重的碘缺乏会影响胎儿的大脑发育,并影响以后的认知,包括智商(IQ)得分降低。1然而,怀孕期间轻度至中度缺乏的影响尚不为人所知。对轻度至中度缺碘孕妇的观察性研究结果显示,其后代智商,阅读能力低,2和拼写分数较低。3尽管已在轻度至中度碘缺乏的地区进行了几项妊娠期补充碘的随机对照试验,但它们并未衡量后代的神经发育。
更新日期:2017-11-10
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