Many patients with head and neck squamous cell carcinoma experience recurrence, but little is known about outcome patterns. Leeman et al reviewed 1000 consecutive patients with stage III to IVB oropharyngeal, oral cavity (OCC), laryngeal, or hypopharyngeal cancers who had been definitively treated. By 5 years, local treatment failure was highest among patients with OCC. Overall survival following local regional failure did not differ between groups, but time from distant metastasis to death was significantly shorter among patients with OCC. Treatment failure and survival after recurrence of head and neck cancer are influenced by site of disease.

中文翻译：

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强调

许多头颈部鳞状细胞癌患者会复发，但对结果模式知之甚少。Leeman等人回顾了经过明确治疗的连续1000例III至IVB期口咽癌，口腔癌（OCC），喉癌或下咽癌患者。到5年时，OCC患者中的局部治疗失败率最高。各组局部区域衰竭后的总生存期无差异，但OCC患者从远处转移到死亡的时间明显缩短。头颈部癌复发后的治疗失败和生存受到疾病部位的影响。