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Incomplete excision of cervical precancer as a predictor of treatment failure: a systematic review and meta-analysis.
The Lancet ( IF 168.9 ) Pub Date : 2017-12-01 , DOI: 10.1016/s1470-2045(17)30700-3
Marc Arbyn 1 , Charles W E Redman 2 , Freija Verdoodt 3 , Maria Kyrgiou 4 , Menelaos Tzafetas 4 , Sadaf Ghaem-Maghami 4 , Karl-Ulrich Petry 5 , Simon Leeson 6 , Christine Bergeron 7 , Pekka Nieminen 8 , Jean Gondry 9 , Olaf Reich 10 , Esther L Moss 11
Affiliation  

Incomplete excision of cervical precancer is associated with therapeutic failure and is therefore considered as a quality indicator of clinical practice. Conversely, the risk of preterm birth is reported to correlate with size of cervical excision and therefore balancing the risk of adequate treatment with iatrogenic harm is challenging. We reviewed the literature with an aim to reveal whether incomplete excision, reflected by presence of precancerous tissue at the section margins, or post-treatment HPV testing are accurate predictors of treatment failure.

中文翻译:

宫颈癌前病变不完全切除作为治疗失败的预测指标:系统评价和荟萃分析。

宫颈癌前病变的不完全切除与治疗失败有关,因此被认为是临床实践的质量指标。相反,据报道早产的风险与宫颈切除术的大小相关,因此平衡充分治疗的风险与医源性伤害具有挑战性。我们回顾了文献,目的是揭示不完全切除(由切片边缘癌前组织的存在所反映)或治疗后 HPV 检测是否是治疗失败的准确预测指标。
更新日期:2017-11-30
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