An efficient strategy for the cleavage of the C–N bond of tertiary amines was developed with DTBP as an oxidant, in which the cleaved H atom and amine moiety were successfully transferred to the desired products. This strategy has enabled an efficient palladium-catalyzed hydroaminocarbonylation of alkynes with tertiary amines. Notably, the catalyst loading could be lowered from 5 to 0.1 mol %, which represents the lowest catalyst loading among the reported work on carbonylation via C–N bond activation.

中文翻译：

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通过C–N键裂解，钯催化叔胺与炔烃催化的氢氨基羰基化反应

以DTBP为氧化剂，开发了一种有效的叔胺C–N键断裂的策略，其中已断裂的H原子和胺部分已成功转移到所需的产物中。该策略已使炔烃与叔胺有效地进行钯催化的氢氨基羰基化。值得注意的是，催化剂的负载量可以从5 mol％降低到0.1 mol％，这代表了在报告的通过C–N键活化进行羰基化的最低催化剂负载量。