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tsRNAs: new players in mammalian retrotransposon control.
Cell Research ( IF 44.1 ) Pub Date : 2017-Nov-01 , DOI: 10.1038/cr.2017.109
Yunfang Zhang , Junchao Shi , Qi Chen

A recent study led by Professor Rob Martienssen in Cell showed that 3'-tRNA-derived small RNAs can suppress long terminal repeat retrotransposon activity in mammalian cells by mechanisms independent of DNA-associated epigenetic marks, suggesting how the genome may defend itself from retrotransposon invasion during epigenetic reprogramming.

中文翻译:

tsRNA:哺乳动物逆转座子控制的新角色。

Rob Martienssen教授领导的一项最新研究表明,3'-tRNA衍生的小RNA可以通过独立于DNA相关表观遗传标记的机制抑制哺乳动物细胞中长末端重复反转录转座子的活性,这表明基因组如何保护自己免受反转录转座子的侵袭在表观遗传重编程过程中。
更新日期:2017-11-06
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