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Uncovering protein–protein interactions through a team-based undergraduate biochemistry course
PLOS Biology ( IF 9.8 ) Pub Date : 2017-11-01 , DOI: 10.1371/journal.pbio.2003145
David L. Cookmeyer , Emily S. Winesett , Bashkim Kokona , Adam R. Huff , Sabina Aliev , Noah B. Bloch , Joshua A. Bulos , Irene L. Evans , Christian R. Fagre , Kerilyn N. Godbe , Maryna Khromava , Daniel M. Konstantinovsky , Alexander E. Lafrance , Alexandra J. Lamacki , Robert C. Parry , Jeanne M. Quinn , Alana M. Thurston , Kathleen J. S. Tsai , Aurelio Mollo , Max J. Cryle , Robert Fairman , Louise K. Charkoudian

How can we provide fertile ground for students to simultaneously explore a breadth of foundational knowledge, develop cross-disciplinary problem-solving skills, gain resiliency, and learn to work as a member of a team? One way is to integrate original research in the context of an undergraduate biochemistry course. In this Community Page, we discuss the development and execution of an interdisciplinary and cross-departmental undergraduate biochemistry laboratory course. We present a template for how a similar course can be replicated at other institutions and provide pedagogical and research results from a sample module in which we challenged our students to study the binding interface between 2 important biosynthetic proteins. Finally, we address the community and invite others to join us in making a larger impact on undergraduate education and the field of biochemistry by coordinating efforts to integrate research and teaching across campuses.



中文翻译:

通过基于团队的本科生化学课程探索蛋白质之间的相互作用

我们如何为学生提供一块肥沃的土地,以同时探索基础知识的广度,发展跨学科的解决问题的能力,获得应变能力以及学习作为团队成员的工作?一种方法是在本科生化学课程中整合原始研究。在此社区页面中,我们讨论了跨学科和跨部门的本科生化学实验室课程的开发和实施。我们提供了一个模板,说明如何在其他机构复制类似的课程,并提供了一个样本模块的教学和研究结果,我们在其中挑战我们的学生研究2种重要生物合成蛋白之间的结合界面。最后,

更新日期:2017-12-01
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