The popularity of fragment-based drug discovery (FBDD) is demonstrated by the number of recent successful fragment-to-lead (F2L) publications. This Miniperspective provides a tabulated summary of the F2L literature published in the year 2016, along with discussion of general trends. It uses the same format as our summary of the 2015 literature and is intended to be a resource for both FBDD practitioners and medicinal chemists in general.

中文翻译：

---

2016年从片段到领先的药物化学出版物

基于片段的药物发现（FBDD）的受欢迎程度由最近成功的片段领先（F2L）出版物的数量证明。本微型透视图提供了2016年发布的F2L文献的列表摘要，并讨论了总体趋势。它使用的格式与我们2015年文献摘要的格式相同，旨在为FBDD从业人员和一般药物化学家提供资源。