A copper-catalyzed procedure for the direct synthesis of 1,4-dihydroxy-2-phenylsufonylbenzenes is presented starting from simple quinones and sulfonyl hydrazides. A series of biologically useful FabH inhibitors are obtained in good yields. Both aryl and alkyl substituents are well tolerated in the reaction.

中文翻译：

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苯醌与芳基（烷基）磺酰基肼的羟基磺酰化反应，用于合成1,4-二羟基-2-芳基（烷基）磺酰基苯

从简单的醌和磺酰肼开始，提出了铜催化直接合成1，4-二羟基-2-苯基磺酰苯的方法。以高收率获得了一系列生物学上有用的FabH抑制剂。该反应中芳基和烷基取代基均具有良好的耐受性。