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Synaptic integrative mechanisms for spatial cognition.
Nature Neuroscience ( IF 25.0 ) Pub Date : 2017-Oct-26 , DOI: 10.1038/nn.4652
Christoph Schmidt-Hieber , Matthew F Nolan

Synaptic integrative mechanisms have profound effects on electrical signaling in the brain that, although largely hidden from recording methods that observe the spiking activity of neurons, may be critical for the encoding, storage and retrieval of information. Here we review roles for synaptic integrative mechanisms in the selection, generation and plasticity of place and grid fields, and in related temporal codes for the representation of space. We outline outstanding questions and challenges in the testing of hypothesized models for spatial computation and memory.

中文翻译:

用于空间认知的突触整合机制。

突触整合机制对大脑中的电信号具有深远的影响,尽管很大程度上被观察神经元突波活动的记录方法所掩盖,但对信息的编码,存储和检索而言可能至关重要。在这里,我们回顾了突触整合机制在位置和网格场的选择,生成和可塑性以及在有关空间表示的相关时间代码中的作用。我们概述了在用于空间计算和内存的假设模型的测试中的突出问题和挑战。
更新日期:2017-10-30
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