Subjecting 6-bromoindole to an iridium-catalysed triborylation-diprotodeborylation sequence followed by Chan-Evans-Lam coupling gives 6-bromo-4-methoxyindole in good overall yield. This indole C4−H alkoxylation process was used in a formal synthesis of the natural product breitfussin B.

中文翻译：

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6-溴吲哚的C4-H烷氧基化及其在短纤红素B合成中的应用

对6-溴吲哚进行铱催化的triborylation-diprotodeborylation序列，然后进行Chan-Evans-Lam偶联，得到的6-溴-4-甲氧基吲哚的总收率良好。该吲哚C4-H烷氧基化过程用于天然产物breitfussin B的正式合成中。