In the present work, a dual mode sensor, which was obtained by integrating B, N, S co-doped carbon dots and Fe³⁺ ([email protected]³⁺), was developed for sensing ascorbic acid (AA). The fluorescent signal of [email protected]³⁺ sensor could be enhanced by AA, and a good linear relationship was obtained in the range of 0.1–600 μM with a detection limit down to 0.05 μM. More fascinatingly, the color of the sensor solution gradually changed from blue to red with the increasing concentrations of AA, which allowed establishing a simple colorimetric assay for AA detection in the linear range of 1–110 μM with a detection limit of 0.3 μM. Notably, a paper sensor for the determination of AA was developed with a lowest visual concentration of 1 μM, providing a novel and convenient platform for AA detection. More importantly, cell imaging experiments showed that this sensor can be applied for AA detection in HeLa cell, suggesting this sensing system holds great potential in biosensing and bioimaging.

在目前的工作中，开发了一种通过结合B，N，S共掺杂的碳点和Fe ³⁺（[受电子邮件保护] ³⁺）获得的双模传感器，用于检测抗坏血酸（AA）。[电子邮件保护]的荧光信号³⁺AA可以增强传感器，并且在0.1–600μM的范围内获得了良好的线性关系，检出限低至0.05μM。更令人着迷的是，随着AA浓度的增加，传感器溶液的颜色从蓝色逐渐变为红色，这允许建立一个简单的比色测定法，用于在1–110μM的线性范围内进行AA检测，检测限为0.3μM。值得注意的是，开发了一种用于测定AA的纸质传感器，其最低视觉浓度为1μM，为AA检测提供了新颖便捷的平台。更重要的是，细胞成像实验表明该传感器可用于HeLa细胞中的AA检测，表明该传感系统在生物传感和生物成像方面具有巨大的潜力。